GBLD-345
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
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2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
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| Identifiers | |
| PubChem | CID 4602899 |
| ChemSpider | 3794457 |
| ChEMBL | CHEMBL1339029 |
| Chemical data | |
| Formula | C21H21N5O2 |
| Molar mass | 375.423 g/mol |
| 3D model (Jmol) | Interactive image |
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GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABAA receptor. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]
References[edit]
- ^ Davies LP, Barlin GB, Ireland SJ, Ngu MM (October 1992). "Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors". Biochemical Pharmacology. 44 (8): 1555–61. doi:10.1016/0006-2952(92)90472-U. PMID 1358075.
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