3-Phosphoglyceric acid

3-Phosphoglyceric acid

Names
IUPAC name (2R)-2-Hydroxy-3-phosphonooxypropanoic acid
Identifiers
CAS Number	820-11-1 N
3D model (Jmol)	Interactive image
ChEBI	CHEBI:17794 Y
ChEMBL	ChEMBL1160563 Y
ChemSpider	388326 Y
PubChem	439183
InChI InChI=1S/C3H7O7P/c4-2(3(5)6)1-10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)/t2-/m1/s1 Y Key: OSJPPGNTCRNQQC-UWTATZPHSA-N Y
SMILES C([C@H](C(=O)O)O)OP(=O)(O)O
Properties
Chemical formula	C3H7O7P
Molar mass	186.06 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

3-Phosphoglyceric acid (3PG), or glycerate 3-phosphate (GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, 3-Phosphoglycerate is the product of the spontaneous split of an unstable 6-carbon intermediate formed by CO₂ fixation. Thus, two 3-phosphoglycerate molecules are produced for each molecule of CO₂ fixed.

Glycolysis

1,3-bisphospho-D-glycerate	3-phosphoglycerate kinase		3-phospho-D-glycerate	Phosphoglyceromutase		2-phospho-D-glycerate
	ADP	ATP
	ADP	ATP
	3-phosphoglycerate kinase			Phosphoglyceromutase

Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.

Click on genes, proteins and metabolites below to link to respective articles.

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Glycolysis and Gluconeogenesis edit

Calvin cycle

In the light-independent reactions (also known as the Calvin cycle), two 3-phosphoglycerate molecules are synthesized, one of which continues through the Calvin cycle to be regenerated to RuBP and the other is reduced to form one molecule of glyceraldehyde 3-phosphate (G3P). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.

Amino acid synthesis

Glycerate 3-phosphate is also a precursor for serine, which, in turn, can create cysteine and glycine through the homocysteine cycle.

See also

• 2-Phosphoglyceric acid