Brallobarbital
From Wikipedia, the free encyclopedia
![]() |
|
![]() |
|
Systematic (IUPAC) name | |
---|---|
5-(2-Bromoprop-2-en-1-yl)-5-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
|
|
Identifiers | |
CAS Number | 561-86-4 ![]() |
ATC code | none |
PubChem | CID 68416 |
ChemSpider | 61699 ![]() |
UNII | D0N7A2M3MU ![]() |
ChEMBL | CHEMBL2106093 ![]() |
Synonyms | Brallobarbital |
Chemical data | |
Formula | C10H11BrN2O3 |
Molar mass | 287.110 g/mol |
3D model (Jmol) | Interactive image |
|
|
|
|
![]() ![]() |
Brallobarbital is a barbiturate developed in the 1920s.[1] It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine.[2] The long half-life of this combination of drugs tended to cause a hangover effect the next day,[3] and Vesparax fell into disuse once newer drugs with lesser side effects had been developed.[4]
References[edit]
- ^ US Patent 1869666
- ^ Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)
- ^ Yih TD, Rossum JM. Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication. Xenobiotica. 1976 Jun;6(6):355-62.
- ^ Fischbach R. Efficacy and safety of midazolam and vesparax in treatment of sleep disorders. British Journal of Clinical Pharmacology. 1983;16 Suppl 1:167S-171S.
![]() |
This sedative-related article is a stub. You can help Wikipedia by expanding it. |