Thiobarbital
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Systematic (IUPAC) name | |
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5,5-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
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Clinical data | |
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Routes of administration |
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Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Biological half-life | ? |
Excretion | ? |
Identifiers | |
CAS Number | 77-32-7 ![]() |
ATC code | ?? (WHO) |
PubChem | CID 667509 |
DrugBank | ? ![]() |
ChemSpider | 580885 ![]() |
Chemical data | |
Formula | C8H12N2O2S |
Molar mass | 200.259 |
3D model (Jmol) | Interactive image |
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Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.
Synthesis[edit]
It is of note that although the drug can be prepared by the above route (cf eg thialbarbital), rxn of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.
References[edit]
- ^ Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie. 335 (3): 334. doi:10.1002/jlac.19043350303.
- ^ Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124. doi:10.1039/JR9440000124.
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