GPR12

GPR12
Identifiers
Aliases	GPR12, GPCR12, GPCR21, PPP1R84, G protein-coupled receptor 12
External IDs	MGI: 101909 HomoloGene: 3868 GeneCards: GPR12
Targeted by Drug
	sphingosine 1-phosphate
Gene ontology
Molecular function	• G-protein coupled receptor activity; • signal transducer activity; • phosphatidylcholine binding;
Cellular component	• integral component of membrane; • plasma membrane; • integral component of plasma membrane; • membrane;
Biological process	• G-protein coupled receptor signaling pathway; • cellular calcium ion homeostasis; • signal transduction;
	Sources:Amigo / QuickGO
RNA expression pattern
	More reference expression data
Orthologs
	2835
	14738
	ENSG00000132975
	ENSMUSG00000041468
	P47775
	P35412
	NM_005288
	NM_001010941; NM_008151
	NP_005279
	NP_001010941.1; NP_032177.1
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 12 is a protein that in humans is encoded by the GPR12 gene.^[4]^[5]^[6]

References[edit]

^ "Drugs that physically interact with G protein-coupled receptor 12 view/edit references on wikidata".
^ "Human PubMed Reference:".
^ "Mouse PubMed Reference:".
^ Saeki Y, Ueno S, Mizuno R, Nishimura T, Fujimura H, Nagai Y, Yanagihara T (Jan 1994). "Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system". FEBS Lett. 336 (2): 317–322. doi:10.1016/0014-5793(93)80828-I. PMID 8262253.
^ Song ZH, Modi W, Bonner TI (Feb 1996). "Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors". Genomics. 28 (2): 347–349. doi:10.1006/geno.1995.1154. PMID 8530049.
^ "Entrez Gene: GPR12 G protein-coupled receptor 12".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Uhlenbrock K, Huber J, Ardati A, et al. (2003). "Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells". Cell. Physiol. Biochem. 13 (2): 75–84. doi:10.1159/000070251. PMID 12649592.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–528. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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