Niguldipine

Niguldipine
Names
	IUPAC name 3-3-(4,4-Diphenyl-1-piperidyl)propyl 5-methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Identifiers
CAS Number	113165-32-5
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL41929
ChemSpider	1199
PubChem	1236
UNII	Z81N45O25Z
	InChI InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3 Key: SVJMLYUFVDMUHP-UHFFFAOYSA-N ; InChI=1/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3 Key: SVJMLYUFVDMUHP-UHFFFAOYAB ;
	SMILES [O-][N+](=O)c1cccc(c1)C5C(/C(=O)OC)=C(\N\C(=C5\C(=O)OCCCN4CCC(c2ccccc2)(c3ccccc3)CC4)C)C ;
Properties
Chemical formula	C36H39N3O6
Molar mass	609.71136
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Niguldipine is a calcium channel blocker and a₁-adrenergic receptor antagonist.^[1]

References[edit]

^ Boer R, Grassegger A, Schudt C, Glossmann H (May 1989). "(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 172 (2): 131–45. doi:10.1016/0922-4106(89)90004-7. PMID 2548881.

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