GPR139

GPR139
Identifiers
Aliases	GPR139, GPRg1, PGR3, G protein-coupled receptor 139
External IDs	MGI: 2685341 HomoloGene: 45860 GeneCards: 124274
Targeted by Drug
L-Phenylalanine, L-Tryptophan
Gene ontology Molecular function • G-protein coupled receptor activity • protein dimerization activity • signal transducer activity • neuropeptide receptor activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • phospholipase C-activating G-protein coupled receptor signaling pathway • neuropeptide signaling pathway • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	124274	209776
Ensembl	ENSG00000180269	ENSMUSG00000066197
UniProt	Q6DWJ6	Q80UC8
RefSeq (mRNA)	NM_001002911 NM_001318483	NM_001024138
RefSeq (protein)	NP_001002911.1 NP_001305412.1	NP_001019309.1
Location (UCSC)	Chr 16: 20.03 – 20.07 Mb	Chr 7: 119.14 – 119.18 Mb
PubMed search
Wikidata
View/Edit Human		View/Edit Mouse

Probable G-protein coupled receptor 139 is a protein that in humans is encoded by the GPR139 gene.

Further reading

• Ottolenghi C, Fellous M, Barbieri M, McElreavey K (2002). "Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination.". Genomics. 79 (3): 333–43. doi:10.1006/geno.2002.6711. PMID 11863363. 
• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. 
• Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626. 
• Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.