LP-12

LP-12

Identifiers
IUPAC name 4-(2-diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide
PubChem (CID)	23643664
ChemSpider	22439715 N
Chemical and physical data
Formula	C32H39N3O
Molar mass	481.670 g/mol
3D model (Jmol)	Interactive image
SMILES C5CCc1ccccc1C5NC(=O)CCCCCN3CCN(CC3)c2ccccc2-c4ccccc4
InChI InChI=1S/C32H39N3O/c36-32(33-30-18-11-15-26-14-6-7-16-28(26)30)20-5-2-10-21-34-22-24-35(25-23-34)31-19-9-8-17-29(31)27-12-3-1-4-13-27/h1,3-4,6-9,12-14,16-17,19,30H,2,5,10-11,15,18,20-25H2,(H,33,36) N Key:NMZIDFFHGCRAJV-UHFFFAOYSA-N N
NY (what is this?)  (verify)

LP-12 is a drug which acts as a potent agonist at the 5HT₇ serotonin receptor, with very high selectivity over other tested receptor subtypes such as the serotonin 5-HT_1A and 5-HT_2A, and the dopamine D₂ receptor. It has been used to research the involvement of the 5-HT₇ receptor in as yet poorly understood processes such as allodynia and hyperalgesia.

See also

• AS-19
• E-55888
• LP-44
• LP-211