CP-226,269
From Wikipedia, the free encyclopedia
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Identifiers | |
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CAS Number | 220941-93-5 ![]() |
PubChem (CID) | 9796720 |
IUPHAR/BPS | 973 |
ChemSpider | 7972486 ![]() |
ChEMBL | CHEMBL77395 ![]() |
Chemical and physical data | |
Formula | C18H19FN4 |
Molar mass | 310.368 g/mol |
3D model (Jmol) | Interactive image |
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CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1][2]
References[edit]
- ^ Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC (May 1999). "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry. 4 (3): 235–46. doi:10.1038/sj.mp.4000522. PMID 10395213.
- ^ Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE (July 2005). "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology. 30 (7): 1257–68. doi:10.1038/sj.npp.1300677. PMID 15688083.
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