VUF-8430
From Wikipedia, the free encyclopedia
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| Names | |
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| Preferred IUPAC name
2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester[citation needed]
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| Identifiers | |
98021-17-1  |
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| 3D model (Jmol) | Interactive image |
| Abbreviations | VUF-8430 |
| ChEMBL | ChEMBL1196470 |
| ChemSpider | 2323820  |
| 1274 | |
| PubChem | 3063228 |
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| Properties | |
| C4H11N5S | |
| Molar mass | 161.23 g·mol−1 |
| log P | -1.367 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is ?) |
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| Infobox references | |
VUF-8430 is a histamine agonist[1] selective for the H4 subtype.[2]
References[edit]
- ^ Smith FM, Haskelberg H, Tracey DJ, Moalem-Taylor G (2007). "Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury". Neuroimmunomodulation. 14 (6): 317–25. doi:10.1159/000125048. PMID 18401194.
- ^ Lim, HD; Smits, RA; Bakker, RA; Van Dam, CM; De Esch, IJ; Leurs, R (2006). "Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.". Journal of Medicinal Chemistry. 49 (23): 6650–1. doi:10.1021/jm060880d. PMID 17154494.
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