Tolonidine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Tolonidine
Tolonidine.svg
Names
IUPAC name
N-(2-Chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine
Identifiers
4201-22-3 YesY
3D model (Jmol) Interactive image
ChemSpider 65112 N
KEGG D07168 YesY
PubChem 72138
UNII I4O795Q03O YesY
Properties
C10H12ClN3
Molar mass 209.67538
Pharmacology
C02AC04 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Tolonidine is an antihypertensive.[1][2][3]

See also[edit]

References[edit]

  1. ^ Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung. 25 (10): 1557–61. PMID 1243037. 
  2. ^ Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". Arzneimittel-Forschung. 25 (11): 1802–6. PMID 1243090. 
  3. ^ Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity". Arzneimittel-Forschung. 25 (12): 1926–33. PMID 3186.