Thiethylperazine
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| Clinical data | |
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| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| ATC code | R06AD03 (WHO) |
| Pharmacokinetic data | |
| Protein binding | 60% |
| Identifiers | |
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| CAS Number | 1420-55-9  Y |
| PubChem (CID) | 5440 |
| IUPHAR/BPS | 7306 |
| DrugBank | DB00372 Y |
| ChemSpider | 5245 Y |
| UNII | 8ETK1WAF6R Y |
| KEGG | D02354 Y |
| ChEBI | CHEBI:9544 Y |
| ChEMBL | CHEMBL1378 Y |
| ECHA InfoCard | 100.014.381 |
| Chemical and physical data | |
| Formula | C22H29N3S2 |
| Molar mass | 399.618 g/mol |
| 3D model (Jmol) | Interactive image |
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Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.
Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice.[1]
References[edit]
- ^ Science Daily (September 1, 2011). "Alzheimer Disease: Transport Protein ABCC1 Plays Key Role in Clearing Beta-Amyloid from Brains of Mice.". Retrieved September 1, 2011.
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| Simple piperazines (no additional rings) |
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| Phenylpiperazines |
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| Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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| Antidepressants (TCAs and TeCAs) |
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| Antihistamines |
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