Xamoterol

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Xamoterol
Xamoterol.svg
Clinical data
ATC code C01CX07 (WHO)
Identifiers
CAS Number 81801-12-9 N
PubChem (CID) 155774
IUPHAR/BPS 538
ChemSpider 137213 YesY
UNII 7HE0JQL703 YesY
KEGG D06328 YesY
ChEMBL CHEMBL75753 YesY
Chemical and physical data
Formula C16H25N3O5
Molar mass 339.387 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Xamoterol is a cardiac stimulant. It works by binding to the β1 adrenergic receptor. It is a 3rd generation adrenergic β receptor partial agonist.[1] It provides cardiac stimulation at rest but it acts as a blocker during exercise.[2]

References[edit]

  1. ^ Marlow, HF (1989). "Xamoterol, a β1-adrenoceptor partial agonist: review of the clinical efficacy in heart failure" (PDF). British Journal of Clinical Pharmacology. 28 Suppl 1: 23S–30S. doi:10.1111/j.1365-2125.1989.tb03570.x. PMC 1379873Freely accessible. PMID 2572251. Retrieved 6 March 2016. 
  2. ^ Rang, H.P.; Dale, M.M.; Ritter, J.M.; Moore, P.K. (1999). Pharmacology (5th ed.). Edinburgh; New York: Churchill Livingstone. p. 163. ISBN 0443059748.