AQP8
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| AQP8 | |||||||||||||||||
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| Aliases | AQP8, AQP-8, aquaporin 8 | ||||||||||||||||
| External IDs | MGI: 1195271 HomoloGene: 68166 GeneCards: AQP8 | ||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||
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| Location (UCSC) | Chr 16: 25.22 – 25.23 Mb | Chr 7: 123.46 – 123.47 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
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Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene.[3][4][5]
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.[5]
See also[edit]
References[edit]
- ^ "Human PubMed Reference:".
- ^ "Mouse PubMed Reference:".
- ^ Koyama N, Ishibashi K, Kuwahara M, Inase N, Ichioka M, Sasaki S, Marumo F (Jan 1999). "Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene". Genomics. 54 (1): 169–72. doi:10.1006/geno.1998.5552. PMID 9806845.
- ^ Viggiano L, Rocchi M, Svelto M, Calamita G (Jul 1999). "Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12". Cytogenet Cell Genet. 84 (3–4): 208–10. doi:10.1159/000015260. PMID 10393433.
- ^ a b "Entrez Gene: AQP8 aquaporin 8".
Further reading[edit]
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Harrington DJ, Adachi K, Royer WE (1997). "The high resolution crystal structure of deoxyhemoglobin S". J. Mol. Biol. 272 (3): 398–407. doi:10.1006/jmbi.1997.1253. PMID 9325099.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Fischer H, Stenling R, Rubio C, Lindblom A (2003). "Differential expression of Aquaporin 8 in human colonic epithelial cells and colorectal tumors". BMC Physiol. 1: 1. doi:10.1186/1472-6793-1-1. PMC 32180
. PMID 11231887. - Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Wang S, Kallichanda N, Song W, et al. (2001). "Expression of aquaporin-8 in human placenta and chorioamniotic membranes: evidence of molecular mechanism for intramembranous amniotic fluid resorption". Am. J. Obstet. Gynecol. 185 (5): 1226–31. doi:10.1067/mob.2001.117971. PMID 11717661.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wang S, Chen J, Au KT, Ross MG (2003). "Expression of aquaporin 8 and its up-regulation by cyclic adenosine monophosphate in human WISH cells". Am. J. Obstet. Gynecol. 188 (4): 997–1001. doi:10.1067/mob.2003.214. PMID 12712100.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zahn A, Moehle C, Langmann T, et al. (2007). "Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis". World J. Gastroenterol. 13 (11): 1687–95. PMID 17461471.
External links[edit]
- AQP8 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Human AQP8 genome location and AQP8 gene details page in the UCSC Genome Browser.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
