Ifetroban

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Ifetroban
Ifetroban.svg
Systematic (IUPAC) name
3-[2-({(1S,2R,3S)-3-[4-(Pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid
Identifiers
CAS Number 143443-90-7
PubChem CID 23724921
ChemSpider 58452
UNII E833KT807K YesY
KEGG D04500
ChEMBL CHEMBL2146062
Chemical data
Formula C25H32N2O5
Molar mass 440.53 g/mol
3D model (Jmol) Interactive image

Ifetroban is a potent and selective thromboxane receptor antagonist.[1]

Synthesis[edit]

Ifetroban synthesis: Drugs Future (c.f. Lednicer book 6).

References[edit]

  1. ^ Dockens, RC; Santone, KS; Mitroka, JG; Morrison, RA; Jemal, M; Greene, DS; Barbhaiya, RH (August 2000). "Disposition of Radiolabeled Ifetroban in Rats, Dogs, Monkeys, and Humans" (PDF). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28 (8): 973–80. PMID 10901709. Retrieved 5 October 2016.