Azapropazone
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| Systematic (IUPAC) name | |
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(RS)-5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione
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| Clinical data | |
| Trade names | Rheumox |
| AHFS/Drugs.com | International Drug Names |
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| Pharmacokinetic data | |
| Biological half-life | 20 hours |
| Identifiers | |
| CAS Number | 13539-59-8  |
| ATC code | M01AX04 (WHO) |
| PubChem | CID 26098 |
| ChemSpider | 24310  |
| UNII | K2VOT966ZI |
| KEGG | D02966 |
| ChEBI | CHEBI:38010 |
| ChEMBL | CHEMBL1231131 |
| Chemical data | |
| Formula | C16H20N4O2 |
| Molar mass | 300.36 g/mol |
| Chirality | Racemic mixture |
| 3D model (Jmol) | Interactive image |
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Azapropazone is a non-steroidal anti-inflammatory drug. It is manufactured by Goldshield under the tradename Rheumox.[1]
It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects.[2] Azopropazone has now been discontinued in the British National Formulary.
Azapropazone has a half-life of approximately 20 hours in humans and is not extensively metabolized.[3]
References[edit]
- ^ http://home.intekom.com/pharm/cont_eth/rheumox.html
- ^ http://www.patient.co.uk/showdoc/30002267/
- ^ Jones CJ (1976). "The pharmacology and pharmacokinetics of azapropazone - a review". Curr Med Res Opin. 4 (1): 3–16. doi:10.1185/03007997609109361. PMID 770078.
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