TAS2R46

TAS2R46
Identifiers
Aliases	TAS2R46, T2R46, T2R54, taste 2 receptor member 46
External IDs	MGI: 2681256 HomoloGene: 135705 GeneCards: TAS2R46
Gene ontology
Molecular function	• G-protein coupled receptor activity; • signal transducer activity; • bitter taste receptor activity;
Cellular component	• plasma membrane; • cell projection; • cilium; • membrane; • ciliary membrane; • integral component of membrane;
Biological process	• G-protein coupled receptor signaling pathway; • detection of chemical stimulus involved in sensory perception of bitter taste; • signal transduction; • response to stimulus; • sensory perception of taste;
	Sources:Amigo / QuickGO
Orthologs
	259292
	387348
	n/a
	ENSMUSG00000059382
	P59540
	Q7M721
	NM_176887
	NM_207023
	NP_795368
	NP_996906.1
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.^[3]^[4]

References[edit]

^ "Human PubMed Reference:".
^ "Mouse PubMed Reference:".
^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
^ "Entrez Gene: TAS2R46 taste receptor, type 2, member 46".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction.". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste.". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family.". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes.". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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