GPR15

GPR15
Identifiers
Aliases	GPR15, BOB, G protein-coupled receptor 15
External IDs	MGI: 1918473 HomoloGene: 3869 GeneCards: GPR15
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • T cell migration • G-protein coupled receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2838	71223
Ensembl	ENSG00000154165	ENSMUSG00000047293
UniProt	P49685	Q0VDU3
RefSeq (mRNA)	NM_005290	NM_001162955
RefSeq (protein)	NP_005281	NP_001156427.1
Location (UCSC)	Chr 3: 98.53 – 98.53 Mb	Chr 16: 58.72 – 58.72 Mb
PubMed search
Wikidata
View/Edit Human		View/Edit Mouse

G-protein coupled receptor 15 is a protein that in humans is encoded by the GPR15 gene.

Further reading

• Cunningham AL, Li S, Juarez J, et al. (2000). "The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes". J. Leukoc. Biol. 68 (3): 311–7. PMID 10985245. 
• Deng HK, Unutmaz D, KewalRamani VN, Littman DR (1997). "Expression cloning of new receptors used by simian and human immunodeficiency viruses". Nature. 388 (6639): 296–300. doi:10.1038/40894. PMID 9230441. 
• Farzan M, Choe H, Martin K, et al. (1997). "Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection". J. Exp. Med. 186 (3): 405–11. doi:10.1084/jem.186.3.405. PMC 2198994. PMID 9236192. 
• Clayton F, Kotler DP, Kuwada SK, et al. (2001). "Gp120-Induced Bob/GPR15 Activation : A Possible Cause of Human Immunodeficiency Virus Enteropathy". Am. J. Pathol. 159 (5): 1933–9. doi:10.1016/S0002-9440(10)63040-4. PMC 1867054. PMID 11696454. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Croitoru-Lamoury J, Guillemin GJ, Boussin FD, et al. (2003). "Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation". Glia. 41 (4): 354–70. doi:10.1002/glia.10181. PMID 12555203. 
• Maresca M, Mahfoud R, Garmy N, et al. (2003). "The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line". J. Biomed. Sci. 10 (1): 156–66. doi:10.1159/000068089. PMID 12566994. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Blaak H, Boers PH, Gruters RA, et al. (2005). "CCR5, GPR15, and CXCR6 Are Major Coreceptors of Human Immunodeficiency Virus Type 2 Variants Isolated from Individuals with and without Plasma Viremia". J. Virol. 79 (3): 1686–700. doi:10.1128/JVI.79.3.1686-1700.2005. PMC 544080. PMID 15650194. 
• Cilliers T, Willey S, Sullivan WM, et al. (2005). "Use of alternate coreceptors on primary cells by two HIV-1 isolates". Virology. 339 (1): 136–44. doi:10.1016/j.virol.2005.05.027. PMID 15992849.