Difemetorex
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| Systematic (IUPAC) name | |
|---|---|
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2-[2-(diphenylmethyl)piperidin-1-yl]ethanol
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| Clinical data | |
| Routes of administration |
Oral |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | 13862-07-2 |
| ATC code | none |
| PubChem | CID 65607 |
| ChemSpider | 59048 |
| UNII | O0417MPF6W  Y |
| ChEMBL | CHEMBL2104291 |
| Chemical data | |
| Formula | C20H25NO |
| Molar mass | 295.42 g/mol |
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Difemetorex (INN; sold as Cleofil), also known as diphemethoxidine, is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use.[1][2][3][4][5] It was introduced in France by Ciba-Geigy in 1966 but is now no longer marketed.[6]
See also[edit]
References[edit]
- ^ Isbell H, Chrusciel TS. Dependence Liability of Non-Narcotic Drugs. Bulletin of the World Health Organisation 1970; 43: Supplement.
- ^ Stepanek, J; Zolliker, VR (1971). "Circulatory effects of the anorectic Diphemethoxidine compared with the effects of Amphetamine and Aminorex". Archives Internationales de Pharmacodynamie et de Thérapie. 191 (2): 376–99. PMID 5089225.
- ^ Stepanek, J (1972). "Alteration of the acid-base equilibrium by the anorectic diphemethoxidine in comparison with the effect of amphetamine and aminorex". Archives Internationales de Pharmacodynamie et de Thérapie. 199 (1): 122–38. PMID 5072180.
- ^ Hall, Judith A.; Morton, Ian (1999). Concise dictionary of pharmacological agents: properties and synonyms. Kluwer Academic. ISBN 0-7514-0499-3.
- ^ "The use of common stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Retrieved 2010-03-23.
- ^ Brudon, Pascale (1983). Médicaments pour tous en l'an 2000?: les multinationales pharmaceutiques suisses face au tiers monde : l'exemple du Mexique. France: Editions d'En bas. p. 207. ISBN 2-8290-0039-0.
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