JWH-030

From Wikipedia, the free encyclopedia
Jump to: navigation, search
JWH-030
JWH-030.svg
Identifiers
CAS Number 162934-73-8 YesY
PubChem (CID) 9971539
ChemSpider 8147131
ChEMBL CHEMBL71810
Chemical and physical data
Formula C20H21NO
Molar mass 291.386 g/mol
3D model (Jmol) Interactive image
  (verify)

JWH-030 is a research chemical which is a cannabinoid receptor agonist.[1] It has analgesic effects and is used in scientific research.[2] It is a partial agonist at CB1 receptors, with a Ki of 87nM, making it roughly half the potency of THC.[3] It was discovered and named after Dr. John W. Huffman.

See also[edit]

References[edit]

  1. ^ Lainton JAH, Huffman JW, Martin BR, Compton DR. Tetrahedron Letters. 1995; 36:1401.
  2. ^ Pertwee RG, Griffin, G, Lainton JAH, Huffman JW. European Journal of Pharmacology. 1995; 284:241.
  3. ^ Griffin, G.; Atkinson, P. J.; Showalter, V. M.; Martin, B. R.; Abood, M. E. (1998). "Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-35Sthio)-triphosphate binding assay in rat cerebellar membranes". The Journal of Pharmacology and Experimental Therapeutics. 285 (2): 553–560. PMID 9580597.