AMB-FUBINACA
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| CAS Number | 1715016-76-4(racemate) |
| PubChem (CID) | 119026173 |
| ChemSpider | 32741679 |
| UNII | TY9AKI870R |
| Chemical and physical data | |
| Formula | C21H22FN3O3 |
| Molar mass | 383.42 g/mol |
| 3D model (Jmol) | Interactive image |
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AMB-FUBINACA (also known as FUB-AMB and MMB-FUBINACA) is an indazole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1][2][3] It was originally developed by Pfizer which described the compound in a patent in 2009, but was later abandoned and never tested on humans.[4]
Mass casualties[edit]
On July 12, 2016 the New York City Emergency Medical Services (EMS) responded[5] to a "mass casualty event" in Brooklyn, New York, [6] where 33 people ranging in age from 25 to 59 years old were adversely affected by the drug.[5] 18 were hospitalized.[5] All of the victims were described by by- standers as “zombielike” and the cause was attributed to use of AMB-FUBINACA.[5]
Legal status[edit]
The state of Louisiana banned AMB-FUBINACA through an emergency rule after it was detected in a synthetic cannabis product called "Train Wreck 2" which had been linked to adverse events and seizures on 3 June 2014.[7]
Sweden's public health agency suggested classifying AMB-FUBINACA as a hazardous substance on November 10, 2014.[8]
See also[edit]
References[edit]
- ^ "FUB-AMB". Cayman Chemical. Retrieved 21 July 2015.
- ^ Shigeki Akamatsu; Masashi Yoshida (January 2016). "Fragmentation of synthetic cannabinoids with an isopropyl group or a tert-butyl group ionized by electron impact and electrospray". Journal of Mass Spectrometry. 51 (1): 28–32. doi:10.1002/jms.3722.
- ^ Samuel D Banister; et al. (July 2016). "The pharmacology of valinate and tert-leucinate synthetic cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and their analogues". ACS Chemical Neuroscience. doi:10.1021/acschemneuro.6b00137.
- ^ Santora, Marc (2016-12-14). "Drug 85 Times as Potent as Marijuana Caused a 'Zombielike' State in Brooklyn". The New York Times. ISSN 0362-4331. Retrieved 2016-12-15.
- ^ a b c d Adams, Axel J.; Banister, Samuel D.; Irizarry, Lisandro; Trecki, Jordan; Schwartz, Michael; Gerona, Roay (14 December 2016). ""Zombie" Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York" (PDF). New England Journal of Medicine. doi:10.1056/NEJMoa1610300. Retrieved 15 December 2016.
- ^ Santora, Mark. "Drug 85 Times as Potent as Marijuana Caused a 'Zombielike' State in Brooklyn". New York Times. Retrieved 15 December 2016.
- ^ "DHH Adds Two New Synthetic Marijuana Compounds to Banned List". Louisiana Department of Health and Hospitals. 3 June 2014. Retrieved 21 July 2015.
- ^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. Retrieved 21 July 2015.
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