Quipazine
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Clinical data | |
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ATC code | none |
Identifiers | |
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CAS Number | 4774-24-7 Y |
PubChem (CID) | 5011 |
IUPHAR/BPS | 173 |
ChemSpider | 4836 N |
UNII | 4WCY05C0SJ N |
ChEMBL | CHEMBL18772 N |
Chemical and physical data | |
Formula | C13H15N3 |
Molar mass | 213.278 g/mol |
3D model (Jmol) | Interactive image |
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NY (what is this?) (verify) |
Quipazine is a piperazine drug used in scientific research. It is a moderately selective serotonin receptor receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5-HT2A[1] and 5-HT3.[2]
References[edit]
- ^ Smith, R. L.; Barrett, R. J.; Sanders-Bush, E (1995). "Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor". The Journal of pharmacology and experimental therapeutics. 275 (2): 1050–7. PMID 7473132.
- ^ Cappelli, A; Anzini, M; Vomero, S; Mennuni, L; Makovec, F; Doucet, E; Hamon, M; Bruni, G; Romeo, M. R.; Menziani, M. C.; De Benedetti, P. G.; Langer, T (1998). "Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives". Journal of Medicinal Chemistry. 41 (5): 728–41. doi:10.1021/jm970645i. PMID 9513601.
Simple piperazines (no additional rings) |
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Phenylpiperazines |
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Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolylpiperazines | |
Tricyclics (piperazine attached via side chain) |
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Others/Uncategorized |
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