Ro10-5824

Ro10-5824
Identifiers
	IUPAC name 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;
CAS Number	189744-46-5
PubChem (CID)	16759175
ChemSpider	14016802
ChEMBL	CHEMBL1616116
Chemical and physical data
Formula	C17H20N4
Molar mass	280.367 g/mol
3D model (Jmol)	Interactive image
	SMILES c3ccccc3C(=CC2)CCN2Cc1cnc(C)nc1N ;
	InChI InChI=1S/C17H20N4/c1-13-19-11-16(17(18)20-13)12-21-9-7-15(8-10-21)14-5-3-2-4-6-14/h2-7,11H,8-10,12H2,1H3,(H2,18,19,20) ; Key:KABDATZAOUSYES-UHFFFAOYSA-N ;
(verify)

Ro10-5824 is a drug which acts as a dopamine receptor partial agonist selective for the D₄ subtype, and has nootropic effects in animal studies.^[1]^[2]

References[edit]

^ Powell SB, Paulus MP, Hartman DS, Godel T, Geyer MA (March 2003). "RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice". Neuropharmacology. 44 (4): 473–81. doi:10.1016/S0028-3908(02)00412-4. PMID 12646284.
^ Newman-Tancredi A, Heusler P, Martel JC, Ormière AM, Leduc N, Cussac D (May 2008). "Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells". The International Journal of Neuropsychopharmacology. 11 (3): 293–307. doi:10.1017/S1461145707008061. PMID 17897483.

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.