2-Methyl-5-hydroxytryptamine
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Identifiers | |
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CAS Number | 78263-90-8 N |
PubChem (CID) | 1574 |
IUPHAR/BPS | 218 |
ChemSpider | 1518 Y |
KEGG | C13665 Y |
ChEBI | CHEBI:31085 Y |
ChEMBL | CHEMBL266591 Y |
Chemical and physical data | |
Formula | C11H14N2O |
Molar mass | 190.242 g/mol |
3D model (Jmol) | Interactive image |
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NY (what is this?) (verify) |
2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor.[1][2][3]
See also[edit]
References[edit]
- ^ Elz S, Zimmermann H, Rehse K (1993). "Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.". Arch Pharm (Weinheim). 326 (11): 893–899. doi:10.1002/ardp.19933261110. PMID 8274071.
- ^ Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE (1990). "5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.". Naunyn Schmiedebergs Arch Pharmacol. 342 (1): 9–16. doi:10.1007/bf00178965. PMID 2402303.
- ^ Glennon RA, Dukat M, Westkaemper RB (2000-01-01). "Serotonin Receptor Subtypes and Ligands". American College of Neurophyscopharmacology. Archived from the original on 21 April 2008. Retrieved 2008-04-11.
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