LP-12

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LP-12
LP-12 structure.png
Identifiers
PubChem (CID) 23643664
ChemSpider 22439715 N
Chemical and physical data
Formula C32H39N3O
Molar mass 481.670 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

LP-12 is a drug which acts as a potent agonist at the 5HT7 serotonin receptor, with very high selectivity over other tested receptor subtypes such as the serotonin 5-HT1A and 5-HT2A, and the dopamine D2 receptor. It has been used to research the involvement of the 5-HT7 receptor in as yet poorly understood processes such as allodynia and hyperalgesia.[1]

See also[edit]

References[edit]

  1. ^ Godínez-Chaparro B, Barragán-Iglesias P, Castañeda-Corral G, Rocha-González HI, Granados-Soto V (March 2011). "Role of peripheral 5-HT(4), 5-HT(6), and 5-HT(7) receptors in development and maintenance of secondary mechanical allodynia and hyperalgesia". Pain. 152 (3): 687–97. doi:10.1016/j.pain.2010.12.020. PMID 21239110.