βk-2C-B

Βk-2C-B
Clinical data
Routes of; administration	Oral
Legal status
Legal status	CA: Schedule III controlled substance; Illegal in Sweden and Switzerland;
Identifiers
CAS Number	807631-09-0
PubChem	CID 11288812
ChemSpider	9463799
UNII	W6KJ195I24
Chemical and physical data
	Systematic (IUPAC) name: 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan-1-one
3D model (Jmol)	Interactive image
Formula	C10H12BrNO3
Molar mass	274.111 g/mol (freebase); 310.572 g/mol (HCl salt)
	SMILES COC1=CC(C(=O)CN)=C(OC)C=C1Br ;
	InChI InChI=InChI=1S/C10H12BrNO3/c1-14-9-4-7(11)10(15-2)3-6(9)8(13)5-12/h3-4H,5,12H2,1-2H3 ; Key:HFYJGAIOBIDRPX-UHFFFAOYSA-N ;

βk-2C-B (beta-keto 2C-B, bk-2C-B) is a psychedelic drug which is structurally related to 2C-B and BOB^[1] and has been sold online as a designer drug.^[2]^[3]

Legal status[edit]

Canada[edit]

On 12 October 2016, βk-2C-B will become a controlled substance (Schedule III) in Canada.^[4]

Europe[edit]

βk-2C-B is illegal in Switzerland,^[5] Sweden^[6] and the United Kingdom^[7]

References[edit]

^ Richard A. Glennon; Mikhail L. Bondarev; Nantaka Khorana; Richard Young; Jesse A. May; Mark R. Hellberg; Marsha A. McLaughlin; Najam A. Sharif (November 2004). "β-Oxygenated Analogues of the 5-HT_2A Serotonin Receptor Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane". Journal of Medicinal Chemistry. 47 (24): 6034–6041. doi:10.1021/jm040082s. PMID 15537358.
^ John D. Power; Pierce Kavanagh; John O'Brien; Michael Barry; Brendan Twamley; Brian Talbot; Geraldine Dowling; Simon D. Brandt (June 2015). "Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B)". Drug Testing and Analysis. 7 (6): 512–518. doi:10.1002/dta.1699. PMID 25078895.
^ Giampietro Frison; Sara Odoardi; Samuela Frasson; Rocco Sciarrone; Giorgio Ortar; Francesco Saverio Romolo; Sabina Strano Rossi (July 2015). "Characterization of the designer drug bk-2C-B (2-amino-1-(bromo-dimethoxyphenyl)ethan-1-one) by gas chromatography/mass spectrometry without and with derivatization with 2,2,2-trichloroethyl chloroformate, liquid chromatography/high-resolution mass spectrometry, and nuclear magnetic resonance". Rapid Communications in Mass Spectrometry. 29 (13): 1196–1204. doi:10.1002/rcm.7211. PMID 26395784.
^ "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Controlled Substances Act.
^ "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Der Bundesrat.
^ "Nya substanser klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 18 August 2015.
^ "Psychoactive Substances Act 2016". Home Office. Retrieved 8 September 2016.

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[1] Richard A. Glennon; Mikhail L. Bondarev; Nantaka Khorana; Richard Young; Jesse A. May; Mark R. Hellberg; Marsha A. McLaughlin; Najam A. Sharif (November 2004). "β-Oxygenated Analogues of the 5-HT_2A Serotonin Receptor Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane". Journal of Medicinal Chemistry. 47 (24): 6034–6041. doi:10.1021/jm040082s. PMID 15537358.

[2] John D. Power; Pierce Kavanagh; John O'Brien; Michael Barry; Brendan Twamley; Brian Talbot; Geraldine Dowling; Simon D. Brandt (June 2015). "Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B)". Drug Testing and Analysis. 7 (6): 512–518. doi:10.1002/dta.1699. PMID 25078895.

[3] Giampietro Frison; Sara Odoardi; Samuela Frasson; Rocco Sciarrone; Giorgio Ortar; Francesco Saverio Romolo; Sabina Strano Rossi (July 2015). "Characterization of the designer drug bk-2C-B (2-amino-1-(bromo-dimethoxyphenyl)ethan-1-one) by gas chromatography/mass spectrometry without and with derivatization with 2,2,2-trichloroethyl chloroformate, liquid chromatography/high-resolution mass spectrometry, and nuclear magnetic resonance". Rapid Communications in Mass Spectrometry. 29 (13): 1196–1204. doi:10.1002/rcm.7211. PMID 26395784.

[4] "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Controlled Substances Act.

[5] "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Der Bundesrat.

[6] "Nya substanser klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 18 August 2015.

[7] "Psychoactive Substances Act 2016". Home Office. Retrieved 8 September 2016.

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v t e Phenethylamines

Phenethylamines	Psychedelics: 25B-NBOMe 25C-NBOMe 25D-NBOMe 25I-NBOMe 25N-NBOMe 2C-B 2C-B-AN 2C-B-FLY βk-2C-B 2C-C 2C-D 2C-E 2C-EF 2C-F 2C-G 2C-I 2C-N 2C-P 2C-SE 2C-T 2C-T-2 2C-T-4 2C-T-7 2C-T-8 2C-T-9 2C-T-13 2C-T-15 2C-T-16 2C-T-17 2C-T-21 2C-TFM 2C-YN Allylescaline DESOXY Escaline Isoproscaline Jimscaline Macromerine MEPEA Mescaline Metaescaline Methallylescaline Proscaline Psi-2C-T-4 TCB-2 Stimulants: Phenylethanolamine Hordenine Phenethylamine α-Methylphenethylamine (amphetamine) β-Methylphenethylamine m-Methylphenethylamine N-Methylphenethylamine o-Methylphenethylamine p-Methylphenethylamine Entactogens: Lophophine MDPEA MDMPEA Others: BOH DMPEA

Amphetamines	Psychedelics: 3C-BZ 3C-E 3C-P Aleph Beatrice Bromo-DragonFLY D-Deprenyl DMA DMCPA DMMDA DOB DOC DOEF DOET DOI DOM DON DOPR DOTFM Ganesha MMDA MMDA-2 Psi-DOM TMA TeMA Stimulants: 2-FA 2-FMA 3-FA 3-FMA Acridorex Alfetamine Amfecloral Amfepentorex Amphetamine (Dextroamphetamine, Levoamphetamine) Amphetaminil Benfluorex Benzphetamine Cathine Clobenzorex Dimethylamphetamine Ephedrine Etilamfetamine Fencamfamine Fencamine Fenethylline Fenfluramine (Dexfenfluramine, Levofenfluramine) Fenproporex Flucetorex Fludorex Formetorex Furfenorex Gepefrine 4-Hydroxyamphetamine Iofetamine Isopropylamphetamine Lefetamine Lisdexamfetamine Mefenorex Metaraminol Methamphetamine (Dextromethamphetamine, Levomethamphetamine) Methoxyphenamine MMA Morforex Norfenfluramine L -Norpseudoephedrine N,alpha-Diethylphenylethylamine Oxifentorex Oxilofrine Ortetamine PBA PCA Phenpromethamine PFA PFMA PIA PMA PMEA PMMA Phenylpropanolamine Pholedrine Prenylamine Propylamphetamine Pseudoephedrine Sibutramine Tiflorex Tranylcypromine Xylopropamine Zylofuramine Entactogens: 4-FA 4-FMA 4-MA 4-MMA 4-MTA 5-APB 5-APDB 5-EAPB 5-IT 5-MAPB 5-MAPDB 6-APB 6-APDB 6-Chloro-MDMA 6-EAPB 6-IT 6-MAPB 6-MAPDB EDA IAP 2,3-MDA 3,4-MDA MDEA MDHMA MDMA MDOH Methamnetamine MMDMA Naphthylaminopropane TAP Others: 3,4-DCA Amiflamine DFMDA Selegiline (also D -Deprenyl)

Phentermines	Stimulants: Chlorphentermine Cloforex Clortermine Etolorex Mephentermine Pentorex Phentermine Entactogens: MDPH MDMPH Others: Cericlamine

Cathinones	Stimulants: 3-FMC 4-MC 4-BMC 4-CMC 4-EMC 4-FMC 4-MEC 4-MeMABP 4-MPD Amfepramone Benzedrone Brephedrone Buphedrone Bupropion Cathinone Dimethylcathinone Ethcathinone Eutylone Hydroxybupropion Methcathinone Methedrone NEB Pentedrone Pentylone Radafaxine Entactogens: 3,4-DMMC 3-MMC Butylone Ethylone Methylone Methylenedioxycathinone Mephedrone

Phenylisobutylamines	Entactogens: 4-CAB 4-MAB Ariadne BDB Butylone EBDB Eutylone MBDB Stimulants: Phenylisobutylamine

Phenylalkylpyrrolidines	Stimulants: α-PBP α-PHP α-PPP α-PVP MDPBP MDPPP MDPV 4-MePBP 4-MePHP 4-MePPP MOPPP MOPVP MPBP MPHP MPPP Naphyrone PEP Prolintane Pyrovalerone

Catecholamines (and close relatives)	6-FNE 6-OHDA a-Me-DA a-Me-TRA Adrenochrome Ciladopa D -DOPA (Dextrodopa) Dimetofrine Dopamine Epinephrine Epinine Etilefrine Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L -DOPA (Levodopa) L -DOPS (Droxidopa) L -Phenylalanine L -Tyrosine m-Tyramine Metanephrine Metaraminol Metaterol Metirosine Methyldopa N,N-Dimethyldopamine Nordefrin (Levonordefrin) Norepinephrine Norfenefrine (m-Octopamine) Normetanephrine Orciprenaline p-Octopamine p-Tyramine Phenylephrine Synephrine

Miscellaneous	AL-LAD Amidephrine Arbutamine Cafedrine Denopamine Desvenlafaxine Diphenidine Dizocilpine Dobutamine Dopexamine Ephenidine Etafedrine ETH-LAD Famprofazone Fluorolintane Hexapradol IP-LAD Lysergic acid amide Lysergic acid 2-butyl amide Lysergic acid 2,4-dimethylazetidide Lysergic acid diethylamide Methoxamine Methoxphenidine MT-45 PARGY-LAD Phenibut PRO-LAD Pronethalol Salbutamol (Levosalbutamol) Theodrenaline Thiamphenicol UWA-101

βk-2C-B

Contents

Legal status[edit]

Canada[edit]

Europe[edit]

See also[edit]

References[edit]

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Clinical data

Routes of administration	Oral
Legal status
Legal status	CA: Schedule III controlled substance Illegal in Sweden and Switzerland
Identifiers
CAS Number	807631-09-0
PubChem	CID 11288812
ChemSpider	9463799
UNII	W6KJ195I24^Y
Chemical and physical data
Systematic (IUPAC) name: 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan-1-one
3D model (Jmol)	Interactive image
Formula	C₁₀H₁₂BrNO₃
Molar mass	274.111 g/mol (freebase) 310.572 g/mol (HCl salt)
SMILES COC1=CC(C(=O)CN)=C(OC)C=C1Br
InChI InChI=InChI=1S/C10H12BrNO3/c1-14-9-4-7(11)10(15-2)3-6(9)8(13)5-12/h3-4H,5,12H2,1-2H3 Key:HFYJGAIOBIDRPX-UHFFFAOYSA-N