ABT-202
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Systematic (IUPAC) name | |
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(R)-1-(pyridin-3-yl)pyrrolidin-3-amine
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Identifiers | |
CAS Number | 309959-34-0 |
PubChem | CID 39220800 |
ChemSpider | 16397614 Y |
Chemical data | |
Formula | C9H13N3 |
Molar mass | 163.219 |
3D model (Jmol) | Interactive image |
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ABT-202 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors and has been researched for use as an analgesic, although it has not passed clinical trials.[1][2][3]
References[edit]
- ^ Jain, K. K. (2004). "Modulators of nicotinic acetylcholine receptors as analgesics". Current opinion in investigational drugs (London, England : 2000). 5 (1): 76–81. PMID 14983978.
- ^ Romanelli, M.; Gratteri, P.; Guandalini, L.; Martini, E.; Bonaccini, C.; Gualtieri, F. (2007). "Central nicotinic receptors: structure, function, ligands, and therapeutic potential". ChemMedChem. 2 (6): 746–767. doi:10.1002/cmdc.200600207. PMID 17295372.
- ^ Xu, Naxing; Kim, Grace E.; Gregg, Hope; Wagdy, Azza; Swaine, Brendan A.; Chang, Min S.; El-Shourbagy, Tawakol A. (September 2004). "Automated 96-well liquid–liquid back extraction liquid chromatography–tandem mass spectrometry method for the determination of ABT-202 in human plasma". Journal of Pharmaceutical and Biomedical Analysis. 36 (1): 189–195. doi:10.1016/j.jpba.2004.05.013.
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