Girisopam
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| Systematic (IUPAC) name | |
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1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
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| Identifiers | |
| CAS Number | 82230-53-3  |
| ATC code | none |
| PubChem | CID 71257 |
| ChemSpider | 64387 |
| UNII | 2LP301A921 |
| ChEMBL | CHEMBL1915065  |
| Chemical data | |
| Formula | C18H17ClN2O2 |
| Molar mass | 328.79 |
| 3D model (Jmol) | Interactive image |
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Girisopam[1] (GYKI-51189) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam[2] and zometapine. It has selective anxiolytic action with no sedative, anticonvulsant or muscle relaxant effects.[3][4][5]
See also[edit]
References[edit]
- ^ US Patent 4322346
- ^ Psychotropics.dk
- ^ Andrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T. Neuropharmacology of a new psychotropic 2,3-benzodiazepine. Arzneimittelforschung. 1987 Oct;37(10):1119-24.
- ^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
- ^ Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M. [(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site. Brain Research. Brain Research Protocols. 1999 Jul;4(2):230-5.
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