Thialbarbital

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Thialbarbital
Thialbarbital.svg
Systematic (IUPAC) name
5-allyl-5-cyclohex-2-en-1-yl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Legal status
Legal status
Identifiers
CAS Number 3546-29-0 N
ATC code none
PubChem CID 3032306
ChemSpider 2297316 YesY
UNII ENV72C33QD YesY
ChEMBL CHEMBL2104657 N
Synonyms Kemithal, 5-(1-cyclohex-2-enyl)-5-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
Chemical data
Formula C13H16N2O2S
Molar mass 264.344 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Thialbarbital (Intranarcon) is a barbiturate derivative invented in the 1960s. It has sedative effects, and was used primarily for induction in surgical anaesthesia. [1] Thialbarbital is short acting and has less of a tendency to induce respiratory depression than other barbiturate derivatives such as pentobarbital. [2]

Synthesis[edit]

Thialbarbital synthesis: Volwiler, Tabern, U.S. Patent 2,153,730 (1939 to Abbott)

See also[edit]

References[edit]

  1. ^ Golovchinsky VB, Plehotkina SI. Difference in the sensitivity of the cerebral cortex and midbrain reticular formation to the action of diethylether and thialbarbital. Brain Research. 1971 Jul 9;30(1):37-47.
  2. ^ Bercovitz AB, Godke RA, Biellier HV, Short CE. Surgical anesthesia in turkeys with thialbarbital sodium. American Journal of Veterinary Research. 1975 Mar;36(3):301-2.