Bucetin
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Systematic (IUPAC) name | |
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N-(4-Ethoxyphenyl)-3-hydroxybutanamide
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Identifiers | |
CAS Number | 1083-57-4 ![]() |
ATC code | N02BE04 (WHO) |
PubChem | CID 14130 |
ChemSpider | 13507 |
UNII | 6M7CVQ8PF8 ![]() |
ChEMBL | CHEMBL1697856 |
Chemical data | |
Formula | C12H17NO3 |
Molar mass | 223.268 g/mol |
3D model (Jmol) | Interactive image |
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Bucetin (INN, BAN) is an analgesic and antipyretic that is no longer marketed.[1][2] Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis.[3] Bucetin was withdrawn from use in 1986 due to renal toxicity.[4]
See also[edit]
References[edit]
- ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 184–. ISBN 978-1-4757-2085-3.
- ^ "WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. December 19, 2013.
- ^ Togei, K; Sano, N; Maeda, T; Shibata, M; Otsuka, H (1987). "Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice". Journal of the National Cancer Institute. 79 (5): 1151–8. doi:10.1093/jnci/79.5.1151. PMID 3479641.
- ^ Fung, M.; Thornton, A.; Mybeck, K.; Wu, J. H.-h.; Hornbuckle, K.; Muniz, E. (2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Drug Information Journal. 35: 293–317. doi:10.1177/009286150103500134.
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