Salicylamide

Salicylamide

Systematic (IUPAC) name
2-hydroxybenzamide
Clinical data
MedlinePlus	a681004
Pharmacokinetic data
Excretion	Renal
Identifiers
CAS Number	65-45-2 Y
ATC code	N02BA05 (WHO) N02BA55 (WHO) (combinations)
PubChem	CID 5147
DrugBank	DB08797 Y
ChemSpider	4963 Y
UNII	EM8BM710ZC Y
ChEBI	CHEBI:32114 Y
ChEMBL	CHEMBL27577 Y
NIAID ChemDB	018403
Chemical data
Formula	C7H7NO2
Molar mass	137.136 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(c1ccccc1O)N
InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10) Y Key:SKZKKFZAGNVIMN-UHFFFAOYSA-N Y
Physical data
Density	1.33 g/cm3
Solubility in water	Soluble in hot water, ether, alcohol, and chloroform. mg/mL (20 °C)
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Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy "PainAid". It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin.

Derivatives

Salicylamide is used in the synthesis of: (or formed part of the core structure for)

Pure Salicylamide is a white or slightly pink crystalline powder

1. labetalol
2. medroxalol
3. Closantel
4. Sulfanthrol
5. Carsalam
6. pentalamide
7. probenzamide
8. Exalamide
9. Fenamifuril
10. Ethosalamide (Etosalamide)
11. Saletamide
12. Letimide
13. Anilamate
14. Eupirone (Eupyron) [5712-95-8].
15. Brosotamide
16. Buclosamide
17. Bensalan
18. Dibromsalan

See also

• 4-Aminosalicylic acid
• Mesalazine
• Salsalate

External links

• Safety MSDS data