Miotine
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Names | |
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IUPAC name
[3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate
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Identifiers | |
4464-16-8 ![]() |
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ChemSpider | 41955 ![]() |
Jmol 3D model | Interactive image |
KEGG | C11763 ![]() |
PubChem | 46093 |
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Properties | |
C12H18N2O2 | |
Molar mass | 222.29 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]
Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]
References[edit]
- ^ "http://www.weizmann.ac.il/sb/faculty_pages/Sussman/papers/2002_Bar-On_Biochem.pdf"
- ^ "http://media.wiley.com/product_data/excerpt/72/04700259/0470025972.pdf"
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