S-45A
S-45A was an American satellite, which was lost in a launch failure in 1961. The satellite was intended to operate in a highly elliptical orbit, from which it was to have provided data on the shape of the ionosphere, and on the Earth's magnetic field. It was part of the Explorer programme, and would have been designated Explorer 12 had it reached orbit. It was the second of two identical satellites to be launched; the first, S-45, had also been lost in a launch failure, earlier in the year.
S-45A was launched aboard a Juno II rocket, serial number AM-19G. It was the final flight of the Juno II. The launch took place from Launch Complex 26B at the Cape Canaveral Air Force Station at 19:48:05 UTC on 24 May 1961. The system which was intended to ignite the second stage malfunctioned, and as a result that stage failed to ignite. The rocket failed to achieve orbit.
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S100A13
S100 calcium-binding protein A13 (S100A13) is a protein that in humans is encoded by the S100A13 gene.
Function
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Interactions
S100A13 has been shown to interact with SYT1 and FGF1.
Pathology
Up-regulation of S100A13 was detected in cystic papillary thyroid carcinoma and association of S100A13 expression and chemotherapy resistance was shown in proteomics study of melanoma.
S100A11
S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene.
Function
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Interactions
S100A11 has been shown to interact with Nucleolin and S100B.
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Further reading
It's (album)
It's is the second mini-album by South Korean boy group Teen Top. The mini-album was released on January 9, 2012 and contains six tracks. "Going Crazy" was used as the promotional track for the mini-album. The mini-album debuted at number 3 on the Gaon Album Chart on January 18, 2012.
Background
With six tracks, the album was produced by Brave Brothers Kang Dong Chul, who took on not only the production, but writing, composition, and mixing processes as well to ensure its high quality.
"It's" is filled with an intro, an instrumental, a remix of the title track, and another three full music tracks. The mini album starts off with Teen Top's self-titled intro before it moves to its title track, "Going Crazy". The songs are followed by "Where's Ma Girl" and the slower "Girl Friend". The mini album then moves on to a R&B version of "Going Crazy" before adding another instrumental of the title track.
Track listing
Chart performance
Their title track, "Going Crazy" was the #1 most downloaded ringtone in Korea early January 2012. On January 20, the weekly mobile ringtone chart on major Korean portal site Nate.com revealed that TEEN TOP’s “Going Crazy” triumphed T-ara‘s “Lovey Dovey” to secure the #1 spot.
Frame (GUI)
A frame, or group box, is a type of box within which a collection of graphical control elements can be grouped as a way to show relationships visually, either because the items are functionally related (such as a radio button), or because they apply to related objects.
In HTML (where frame has another meaning, referring to an individually scrollable portion of a page), this kind of grouping box is called a fieldset after the HTML element of the same name.
In the image to the right, the top frame has no title. The two frames below have titles, and a radio button outside them, presumably to select one or the other. The lower of the two boxes is dimmed, or disabled, indicating its widgets cannot be selected. Note that each of the frames (as well as the area outside of the frames) has a checked radio button, while normally only one of the buttons can be selected.
Note that any widget, including nested frames, can be placed inside of a frame, not merely radio buttons.
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Frame (dance)
Frame is the body shape maintained by dancers during partner dancing. Specifically, frame refers to the shape of the upper body of the dancers relative to the rest of the dancer's body and the body of the dancer's partner.
The frame provides connection between the dance partners, making leading and following possible. A frame is a stable structural combination of both bodies maintained through the dancers' arms and/or legs, and allows the leader to transmit body movement to the follower, and for the follower to suggest ideas to the leader.
Connection occurs in both open and closed dance positions (also called "open frame" and "closed frame"). It is essential in most partner dances, but especially so in modern ballroom dance.
The required frame varies according to the dance—in street Latin style dances such as salsa, arms are held more loosely.
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Frame language
A frame language is a technology used for knowledge representation in artificial intelligence. Frames are stored as ontologies of sets and subsets of the frame concepts. They are similar to class hierarchies in object-oriented languages although their fundamental design goals are different. Frames are focused on explicit and intuitive representation of knowledge where as objects focus on encapsulation and information hiding. Frames originated in AI research and objects primarily in software engineering. However, in practice the techniques and capabilities of frame and object-oriented languages overlap significantly.
Description
Early work on Frames was inspired by psychological research going back to the 1930s that indicated people use stored stereotypical knowledge to interpret and act in new cognitive situations. The term Frame was first used by Marvin Minsky as a paradigm to understand visual reasoning and natural language processing. In these and many other types of problems the potential solution space for even the smallest problem is huge. For example, extracting the phonemes from a raw audio stream or detecting the edges of an object. Things which seem trivial to humans are actually quite complex. In fact how difficult they really were was probably not fully understood until AI researchers began to investigate the complexity of getting computers to solve them.
