Proxibarbital
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Systematic (IUPAC) name | |
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(RS)-5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1H,3H,5H)-trione
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Identifiers | |
CAS Number | 2537-29-3 N |
ATC code | N05CA22 (WHO) |
PubChem | CID 17336 |
ChemSpider | 16406 Y |
Synonyms | Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid |
Chemical data | |
Formula | C10H14N2O4 |
Molar mass | 226.229 g/mol |
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NY (what is this?) (verify) |
Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and in contrast to most barbiturates almost without hypnotic action.[1]
It was also used in the treatment of migraine headaches in a similar manner to butalbital.[2]
Valofane tautomerises to Proxibarbal in vivo.
References[edit]
- ^ Zajdel, P.; Kulig, K.; Zejc, A. (2008). Zejc, A.; Gorczyca, M., eds. Chemia leków, podręcznik dla studentów farmacji i farmaceutów (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.
- ^ Sulman, F. G.; Pfeifer, Y.; Tal, E. (1976). "Migraine therapy by enzyme induction with proxibarbital". Therapie der Gegenwart (in German). 115 (12): 2088–2103. PMID 14412.
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Barbiturates |
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See also: GABAergics
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