Amylocaine
From Wikipedia, the free encyclopedia
Names | |
---|---|
IUPAC name
benzoic acid [1-(dimethylaminomethyl)-1-methylpropyl] ester
|
|
Identifiers | |
644-26-8 | |
ChEMBL | ChEMBL1740065 |
ChemSpider | 10312 |
ECHA InfoCard | 100.010.375 |
Jmol 3D model | Interactive image |
KEGG | D07454 |
PubChem | 10767 |
UNII | QRW683O56T |
|
|
|
|
Properties | |
C14H21NO2 | |
Molar mass | 235.32204 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
|
verify (what is ?) | |
Infobox references | |
Amylocaine was the first synthetic local anesthetic. It was synthesized and patented under the name Stovaine by Ernest Fourneau at the Pasteur Institute in 1903.[1] It used to be used mostly in spinal anesthesia.[2]
Notes and references[edit]
- ^ Fourneau, E. (1904). "Stovaïne, anesthésique local". Bulletin des sciences pharmacologiques. 10: 141-148.
- ^ Debue-Barazer, Christine (2007). "Les Implications scientifiques et industrielles du succès de la Stovaïne : Ernest Fourneau (1872-1949) et la chimie des médicaments en France". Gesnerus 64 (1-2): 24-53.
See also[edit]
- Dimethylaminopivalophenone, an opioid with a similar SAR (an amine that is a sole methylene spacer shorter)
External links[edit]
- Smith, Maurice I.; Hatcher, Robert A. (January 1917). "A Contribution to the Pharmacology of Stovaine". Journal of Pharmacology and Experimental Therapeutics. 9 (4): 231–240.
- Ball, Christine M.; Westhorpe, Rod N. (2004). "Local Anaesthesia after Cocaine". Anaesthesia and Intensive Care. 32 (2): 157. PMID 15957711.
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |