AGN-2979

AGN-2979
Systematic (IUPAC) name
	3-(3-dimethylaminopropyl)-3-(3-methoxyphenyl)-4,4-dimethyl-piperidine-2,6-dione
Identifiers
CAS Number	53873-21-5 103353-87-3 (HCl)
PubChem	CID 40914
ChemSpider	37360
Chemical data
Formula	C19H28N2O3
Molar mass	332.44 g/mol
	SMILES O=C1NC(=O)CC(C1(c2cccc(OC)c2)CCCN(C)C)(C)C ;
	InChI InChI=1S/C19H28N2O3/c1-18(2)13-16(22)20-17(23)19(18,10-7-11-21(3)4)14-8-6-9-15(12-14)24-5/h6,8-9,12H,7,10-11,13H2,1-5H3,(H,20,22,23) ; Key:UJFNSGBGJMRZKS-UHFFFAOYSA-N ;
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AGN-2979 is a tryptophan hydroxylase inhibitor.^[1] It shows antidepressant properties in rodent models of depression.^[1]

References[edit]

^ ^a ^b Gittos MW, Papp M (2001). "Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats.". Eur Neuropsychopharmacol. 11 (5): 351–357. doi:10.1016/S0924-977X(01)00103-1. PMID 11597821.

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