2,3-Bisphosphoglyceric acid

2,3-Bisphosphoglyceric acid (2,3-Bisphosphoglycerate or 2,3-BPG, also known as 2,3-diphosphoglycerate or 2,3-DPG) is a three-carbon isomer of the glycolytic intermediate 1,3-bisphosphoglyceric acid (1,3-BPG). 2,3-BPG is present in human red blood cells (RBC; erythrocyte) at approximately 5 mmol/L. It binds with greater affinity to deoxygenated hemoglobin (e.g. when the red cell is near respiring tissue) than it does to oxygenated hemoglobin (e.g., in the lungs) due to spatial changes: 2,3-BPG (with an estimated size of about 9 angstroms) fits in the deoxygenated hemoglobin configuration (11 angstroms), but not as well in the oxygenated (5 angstroms). It interacts with deoxygenated hemoglobin beta subunits by decreasing their affinity for oxygen, so it allosterically promotes the release of the remaining oxygen molecules bound to the hemoglobin, thus enhancing the ability of RBCs to release oxygen near tissues that need it most. 2,3-BPG is thus an allosteric effector.

DPG

DPG may refer to

Toi

Toi or TOI may refer to:

Toi (song)

"Toi" (English translation: "You") was the Luxembourgish entry in the Eurovision Song Contest 1975, performed in French by Irish singer Geraldine. The entry had a high pedigree, being penned by three authors/composers who had all written/composed previous Eurovision winners. Pierre Cour had been partly responsible for the 1960 winner "Tom Pillibi" and Bill Martin and Phil Coulter had created the 1967 winner "Puppet on a String".

The song is a ballad, with Geraldine telling her lover that "my life doesn't exist without you" and pledging her unending love to him. Geraldine recorded the song in two languages; French and her mother tongue English, the latter as "You".

Another singer with a similar name, Géraldine, represented Switzerland in the 1967 Eurovision Song Contest in Vienna, finishing last with 'nul points', but as John Kennedy O'Connor's The Eurovision Song Contest - The Official History notes, despite the similarity in name, the two singers are unique. This Geraldine later married the song's composer, Phil Coulter.

Toi (name)

Toi is a fairly common man's name in Māori and other Polynesian languages.

The best known men named Toi are the following from Māori legendary history, who are sometimes confused with one another:

The descendants of Toi-kai-rākau are named Te Tini-a-Toi – the many descendants of Toi. In the part of the Bay of Plenty where the Mataatua canoe landed, these descendants were divided into at least 18 groups or hapu. Sometimes also the name Te Tini o Toi is used.