Oklahoma medical researchers find biological ‘good guy’ can threaten embryos

Edit The Oklahoman 14 Jun 2016
The new research could have implications not only for prenatal development but also for treating lymphedema and liver damage resulting from acetaminophen overdose.  ... The OMRF researchers also found liver damage could ensue in embryos when the protein that suppresses plasmin activity — known as CHD4 — was absent. Too much plasmin makes liver blood vessels fragile and prone to bleeding....

A new tool brings personalized medicine closer (EPFL - École Polytechnique Fédérale de Lausanne)

Edit Public Technologies 14 Jun 2016
One of the biggest obstacles in successfully treating metabolic disorders such as diabetes, obesity, fatty liver etc, is the variation in the way patients respond to medication ... The scientists used protein data from mice, which they obtained from a new mass spectrometry technique that Aebersold's group developed, known as SWATH-MS ... For example, some developed metabolic disorders like fatty liver, while others did not....

vTv Therapeutics Presents Positive Results from a Pilot Study of its Glucokinase Activator at American ...

Edit Stockhouse 14 Jun 2016
Data show TTP399 improves glycemic control and insulin resistance without hypoglycemia ... In a poster presentation titled, “TTP399, a Novel, Liver Selective Glucokinase Activator ... Importantly, TTP399 did not induce hypoglycemia or have detrimental effects on plasma lipids, as seen with previous GKAs that do not target the liver ... data in mid-2016.”....

Hepatitis B Virus more prevalent than HIV in donor blood

Edit The Hindu 14 Jun 2016
At a time when doubts are being raised about safe blood transfusion in the country, data from the only Individual Donor-Nucleic Acid Testing (ID-NAT) blood bank at the Bowring and Lady Curzon Hospital here has revealed that Hepatitis B Virus (HBV) is more prevalent in donor blood than HIV in the State ... cirrhosis, liver failure and liver cancer....

vTv Therapeutics Presents Positive Results from a Pilot Study of its Glucokinase Activator at American Diabetes Association 76th Scientific Sessions (VTV Therapeutics Inc)

Edit Public Technologies 14 Jun 2016
Data show TTP399 improves glycemic control and insulin resistance without hypoglycemia ... In a poster presentation titled, 'TTP399, a Novel, Liver Selective Glucokinase Activator ... Importantly, TTP399 did not induce hypoglycemia or have detrimental effects on plasma lipids, as seen with previous GKAs that do not target the liver ... data in mid-2016.'....

Surgeon shortage shows why too few transplants in India

Edit Indian Express 14 Jun 2016
Just about 70 kidney transplant surgeons, 300 who do cornea transplants and a little over 100 liver transplant surgeons carry the flag of transplant surgery in India. The estimated 5,000 kidney transplants, 1,500 liver and 20,000-odd cornea transplants that happen every year in India are less than the requirement, which is partly because of lack of infrastructure ... “Every year about one lakh people die of liver diseases....

Conatus to Present at JMP Securities Life Sciences Conference

Edit Stockhouse 14 Jun 2016
Conatus is a biotechnology company focused on the development and commercialization of novel medicines to treat liver disease. Conatus is developing its lead compound, emricasan, for the treatment of patients with chronic liver disease ... Conatus believes that by reducing the activity of these enzymes, emricasan has the potential to interrupt the disease progression across the spectrum of liver disease....

Conatus to Present at JMP Securities Life Sciences Conference (Conatus Pharmaceuticals Inc)

Edit Public Technologies 14 Jun 2016
Conatus is a biotechnology company focused on the development and commercialization of novel medicines to treat liver disease. Conatus is developing its lead compound, emricasan, for the treatment of patients with chronic liver disease ... Conatus believes that by reducing the activity of these enzymes, emricasan has the potential to interrupt the disease progression across the spectrum of liver disease....

HSE to expand hepatitis C treatment programme

Edit The Irish Times 14 Jun 2016
The HSE has announced plans to extend the national hepatitis C drug treatment programme as part of a strategy to eliminate the disease in Ireland by 2026 ... About 70-80 per cent of those with the virus develop chronic liver disease, while 20-30 per cent develop cirrhosis of the liver, which tends to appear after two or three decades. Patients who develop cirrhosis from hepatitis C are more at risk of developing liver cancer ...  . ....

HSE announces plans to expand hepatitis C treatment programme

Edit The Irish Times 14 Jun 2016
The HSE has announced plans to extend the national hepatitis C drug treatment programme as part of a strategy to eliminate the disease in Ireland by 2026 ... About 70-80 per cent of those with the virus develop chronic liver disease, while 20-30 per cent develop cirrhosis of the liver, which tends to appear after two or three decades. Patients who develop cirrhosis from hepatitis C are more at risk of developing liver cancer ...  . ....

Pupcakes and pawstries delight Pune’s pooches

Edit The Times of India 14 Jun 2016
Surrounded by human and four-legged bum-chums, Rafael 'cut' a cake baked specially for him; a fully-loaded chicken liver one with a yogurt-carrot frosting ... Meanwhile, I use chicken liver in the non-vegetarian cakes, but if the animal is fond of other meats, I customise too," Aarohi informs ... Based on this data, we customise a diet chart for the animal," says Rashee....

Nanobiotix Announces Exercise of Warrants by Capital Venture International

Edit Stockhouse 14 Jun 2016
NanoXray products are compatible with current radiotherapy treatments and are meant to treat potentially a wide variety of solid tumors including soft tissue sarcoma, head and neck cancers, liver cancers, prostate cancer, breast cancer, glioblastoma, etc., via multiple routes of administration ... and liver cancers (HCC and liver metastases)....
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