- published: 07 Sep 2010
- views: 195399
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Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
- published: 07 Sep 2010
- views: 100958
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
- published: 07 Sep 2010
- views: 76416
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, hepatic endothelial cells, stellate (Ito) cells, Kuppfer cells, and cholangiocytes.
- published: 16 Jul 2012
- views: 40283
The Architecture of the Liver
The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepatic lobules. Each lobule consists of a central vein, which acts as a tributary of the hepatic vein and conducts processed blood away from the lobule, surrounded by plates of liver cells. The liver receives blood from two sources, 80 percent, which carries digested food materials, arrives from the intestine via the portal vein and venules; the remaining twenty percent is oxygenated blood from the heart, which enters through the hepatic artery and arterioles. An exchange of materials takes place between the liver cells and the blood, which then passes into the central veins and returns to the general body circulation via the hepatic vein. Sinusoids, spaces between plates of liver cells composed of tributaries of the hepatic artery and portal vein, conduct the blood flow to the central vein. The bile canaliculus carries bile juice from the liver to branches of the bile duct which convey bile from the lobules to the gall bladder. When an adult is at rest, about two and a half pints of blood flow through the liver each minute.
- published: 03 Aug 2007
- views: 257201
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is cannulated with a 23 ga needle, buffer (HBSS) is perfused through the vein, the IVC is cut for drainage, and in subsequent steps (not shown here), the liver is digested with collagenase to liberate hepatocytes.
The mouse is completely anesthetized long before the surgical procedure commences, and all steps are in compliance with IACUC protocols. This is, obviously, non-survival surgery. The entire blood volume of the mouse is replaced by buffer within 30 seconds upon cannulation.
Much more available at www.mouselivercells.com
- published: 17 May 2011
- views: 13281
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-step instructions on the proper way to thaw, plate, and incubate cryopreserved hepatocytes for optimal results.
Reference:
Thawing and Plating Protocol - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Thawing-Cryopreserved-Hepatocytes-Protocol-120815.pdf
Cell Counting Protocol : Trypan Blue Exclusion Method - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Trypan-Blue-Cell-Counting-Protocol.pdf
About Triangle Research Labs:
Since its launch in 2011, Triangle Research Labs, or TRL, has supported scientists by providing high quality hepatocytes for multiple research applications. Based in Research Triangle Park, NC, TRL produces fresh and cryopreserved hepatocytes and hepatic non-parenchymal cells from a variety of species in-house. Additionally, TRL distributes cryopreserved NoSpin HepaRG™ cells and media for Biopredic International, and QuasiVivo® Cell Culture Flow Systems for Kirkstall, Ltd in the US and Canada. TRL utilizes an in-depth understanding of research needs to provide efficient solutions. Visit http://triangleresearchlabs.net/ to learn more.
- published: 28 Jul 2016
- views: 208
Hepatocyte
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass. These cells are involved in:
Structure
The typical hepatocyte is cubical with sides of 20-30 µm, (in comparison, a human hair has a diameter of 17 to 180 µm). The typical volume of a hepatocyte is 3.4 x 10−9 cm3.
Smooth endoplasmic reticulum is abundant in hepatocytes, whereas most cells in the body have only small amounts.
Histology
Hepatocytes display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free ribosomes. Brown lipofuscin granules are also observed (with increasing age) together with irregular unstained areas of cytoplasm; these correspond to cytoplasmic glycogen and lipid stores removed during histological preparation. The average life span of the hepatocyte is 5 months; they are able to regenerate.
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/Hepatocyte
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
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15:01Hepatocytes - Liver Histology - Part 1/7
Hepatocytes - Liver Histology - Part 1/7Hepatocytes - Liver Histology - Part 1/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com -
15:01Hepatocytes - Liver Histology - Part 2/7
Hepatocytes - Liver Histology - Part 2/7Hepatocytes - Liver Histology - Part 2/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com -
9:36Hepatocytes - Liver Histology - Part 3/7
Hepatocytes - Liver Histology - Part 3/7Hepatocytes - Liver Histology - Part 3/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com -
19:15Hepatic Physiology 3: Sinusoids & Surrounding Cells
Hepatic Physiology 3: Sinusoids & Surrounding CellsHepatic Physiology 3: Sinusoids & Surrounding Cells
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, hepatic endothelial cells, stellate (Ito) cells, Kuppfer cells, and cholangiocytes. -
1:17How the Body Works : The Architecture of the Liver
How the Body Works : The Architecture of the LiverHow the Body Works : The Architecture of the Liver
The Architecture of the Liver The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepatic lobules. Each lobule consists of a central vein, which acts as a tributary of the hepatic vein and conducts processed blood away from the lobule, surrounded by plates of liver cells. The liver receives blood from two sources, 80 percent, which carries digested food materials, arrives from the intestine via the portal vein and venules; the remaining twenty percent is oxygenated blood from the heart, which enters through the hepatic artery and arterioles. An exchange of materials takes place between the liver cells and the blood, which then passes into the central veins and returns to the general body circulation via the hepatic vein. Sinusoids, spaces between plates of liver cells composed of tributaries of the hepatic artery and portal vein, conduct the blood flow to the central vein. The bile canaliculus carries bile juice from the liver to branches of the bile duct which convey bile from the lobules to the gall bladder. When an adult is at rest, about two and a half pints of blood flow through the liver each minute. -
14:31Primary mouse hepatocyte isolation
Primary mouse hepatocyte isolation -
0:16Hepatocyte cell
Hepatocyte cellHepatocyte cell
-
0:50Cannulation of mouse portal vein for hepatocyte isolation
Cannulation of mouse portal vein for hepatocyte isolationCannulation of mouse portal vein for hepatocyte isolation
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is cannulated with a 23 ga needle, buffer (HBSS) is perfused through the vein, the IVC is cut for drainage, and in subsequent steps (not shown here), the liver is digested with collagenase to liberate hepatocytes. The mouse is completely anesthetized long before the surgical procedure commences, and all steps are in compliance with IACUC protocols. This is, obviously, non-survival surgery. The entire blood volume of the mouse is replaced by buffer within 30 seconds upon cannulation. Much more available at www.mouselivercells.com -
4:01Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating ProtocolThaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-step instructions on the proper way to thaw, plate, and incubate cryopreserved hepatocytes for optimal results. Reference: Thawing and Plating Protocol - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Thawing-Cryopreserved-Hepatocytes-Protocol-120815.pdf Cell Counting Protocol : Trypan Blue Exclusion Method - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Trypan-Blue-Cell-Counting-Protocol.pdf About Triangle Research Labs: Since its launch in 2011, Triangle Research Labs, or TRL, has supported scientists by providing high quality hepatocytes for multiple research applications. Based in Research Triangle Park, NC, TRL produces fresh and cryopreserved hepatocytes and hepatic non-parenchymal cells from a variety of species in-house. Additionally, TRL distributes cryopreserved NoSpin HepaRG™ cells and media for Biopredic International, and QuasiVivo® Cell Culture Flow Systems for Kirkstall, Ltd in the US and Canada. TRL utilizes an in-depth understanding of research needs to provide efficient solutions. Visit http://triangleresearchlabs.net/ to learn more. -
1:22Necrosis of Hepatocyte HD
Necrosis of Hepatocyte HD
-
Hepatocytes - Liver Histology - Part 1/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010 -
Hepatocytes - Liver Histology - Part 2/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010 -
Hepatocytes - Liver Histology - Part 3/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010 -
Hepatic Physiology 3: Sinusoids & Surrounding Cells
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, hepatic endothelial cells, stellate (Ito) cells, Kuppfer cells, and cholangiocytes.
published: 16 Jul 2012 -
How the Body Works : The Architecture of the Liver
The Architecture of the Liver The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepatic lobules. Each lobule consists of a central vein, which acts as a tributary of the hepatic vein and conducts processed blood away from the lobule, surrounded by plates of liver cells. The liver receives blood from two sources, 80 percent, which carries digested food materials, arrives from the intestine via the portal vein and venules; the remaining twenty percent is oxygenated blood from the heart, which enters through the hepatic artery and arterioles. An exchange of materials takes place between the liver cells and the blood, which then passes into the central veins and returns to the general body circulation via the hepatic...
published: 03 Aug 2007 -
-
Hepatocyte cell
published: 09 Oct 2015 -
Cannulation of mouse portal vein for hepatocyte isolation
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is cannulated with a 23 ga needle, buffer (HBSS) is perfused through the vein, the IVC is cut for drainage, and in subsequent steps (not shown here), the liver is digested with collagenase to liberate hepatocytes. The mouse is completely anesthetized long before the surgical procedure commences, and all steps are in compliance with IACUC protocols. This is, obviously, non-survival surgery. The entire blood volume of the mouse is replaced by buffer within 30 seconds upon cannulation. Much more available at www.mouselivercells.com
published: 17 May 2011 -
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-step instructions on the proper way to thaw, plate, and incubate cryopreserved hepatocytes for optimal results. Reference: Thawing and Plating Protocol - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Thawing-Cryopreserved-Hepatocytes-Protocol-120815.pdf Cell Counting Protocol : Trypan Blue Exclusion Method - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Trypan-Blue-Cell-Counting-Protocol.pdf About Triangle Research Labs: Since its launch in 2011, Triangle Research Labs, or TRL, has supported scientists by providing high quality hepatocytes for multiple research applications. Based in Research Triangle P...
published: 28 Jul 2016 -
Hepatocytes - Liver Histology - Part 1/7
- Order: Reorder
- Duration: 15:01
- Updated: 07 Sep 2010
- views: 195399
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
- published: 07 Sep 2010
- views: 195399
Hepatocytes - Liver Histology - Part 2/7
- Order: Reorder
- Duration: 15:01
- Updated: 07 Sep 2010
- views: 100958
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
- published: 07 Sep 2010
- views: 100958
Hepatocytes - Liver Histology - Part 3/7
- Order: Reorder
- Duration: 9:36
- Updated: 07 Sep 2010
- views: 76416
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
- published: 07 Sep 2010
- views: 76416
Hepatic Physiology 3: Sinusoids & Surrounding Cells
- Order: Reorder
- Duration: 19:15
- Updated: 16 Jul 2012
- views: 40283
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, h...
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, hepatic endothelial cells, stellate (Ito) cells, Kuppfer cells, and cholangiocytes.
https://wn.com/Hepatic_Physiology_3_Sinusoids_Surrounding_Cells
Physiology lecture on the liver. Includes a discussion the the structure and function of the sinusoids, and the function of liver cells including hepatocytes, hepatic endothelial cells, stellate (Ito) cells, Kuppfer cells, and cholangiocytes.
- published: 16 Jul 2012
- views: 40283
How the Body Works : The Architecture of the Liver
- Order: Reorder
- Duration: 1:17
- Updated: 03 Aug 2007
- views: 257201
The Architecture of the Liver
The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepat...
The Architecture of the Liver
The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepatic lobules. Each lobule consists of a central vein, which acts as a tributary of the hepatic vein and conducts processed blood away from the lobule, surrounded by plates of liver cells. The liver receives blood from two sources, 80 percent, which carries digested food materials, arrives from the intestine via the portal vein and venules; the remaining twenty percent is oxygenated blood from the heart, which enters through the hepatic artery and arterioles. An exchange of materials takes place between the liver cells and the blood, which then passes into the central veins and returns to the general body circulation via the hepatic vein. Sinusoids, spaces between plates of liver cells composed of tributaries of the hepatic artery and portal vein, conduct the blood flow to the central vein. The bile canaliculus carries bile juice from the liver to branches of the bile duct which convey bile from the lobules to the gall bladder. When an adult is at rest, about two and a half pints of blood flow through the liver each minute.
https://wn.com/How_The_Body_Works_The_Architecture_Of_The_Liver
The Architecture of the Liver
The liver is the largest organ in the body. Liver tissue is composed of a compact mass of multisided units, known as the hepatic lobules. Each lobule consists of a central vein, which acts as a tributary of the hepatic vein and conducts processed blood away from the lobule, surrounded by plates of liver cells. The liver receives blood from two sources, 80 percent, which carries digested food materials, arrives from the intestine via the portal vein and venules; the remaining twenty percent is oxygenated blood from the heart, which enters through the hepatic artery and arterioles. An exchange of materials takes place between the liver cells and the blood, which then passes into the central veins and returns to the general body circulation via the hepatic vein. Sinusoids, spaces between plates of liver cells composed of tributaries of the hepatic artery and portal vein, conduct the blood flow to the central vein. The bile canaliculus carries bile juice from the liver to branches of the bile duct which convey bile from the lobules to the gall bladder. When an adult is at rest, about two and a half pints of blood flow through the liver each minute.
- published: 03 Aug 2007
- views: 257201
Primary mouse hepatocyte isolation
- Order: Reorder
- Duration: 14:31
- Updated: 17 Nov 2011
- views: 23318
Primary mouse hepatocytes isolation by two step collagenase perfusion method...(www.mouselivercells.com)
Primary mouse hepatocytes isolation by two step collagenase perfusion method...(www.mouselivercells.com)
https://wn.com/Primary_Mouse_Hepatocyte_Isolation
Hepatocyte cell
- Order: Reorder
- Duration: 0:16
- Updated: 09 Oct 2015
- views: 417
- published: 09 Oct 2015
- views: 417
Cannulation of mouse portal vein for hepatocyte isolation
- Order: Reorder
- Duration: 0:50
- Updated: 17 May 2011
- views: 13281
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is c...
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is cannulated with a 23 ga needle, buffer (HBSS) is perfused through the vein, the IVC is cut for drainage, and in subsequent steps (not shown here), the liver is digested with collagenase to liberate hepatocytes.
The mouse is completely anesthetized long before the surgical procedure commences, and all steps are in compliance with IACUC protocols. This is, obviously, non-survival surgery. The entire blood volume of the mouse is replaced by buffer within 30 seconds upon cannulation.
Much more available at www.mouselivercells.com
https://wn.com/Cannulation_Of_Mouse_Portal_Vein_For_Hepatocyte_Isolation
This clip details the first step in the surgical procedure for isolation of primary hepatocytes, following exposure of the internal organs. The portal vein is cannulated with a 23 ga needle, buffer (HBSS) is perfused through the vein, the IVC is cut for drainage, and in subsequent steps (not shown here), the liver is digested with collagenase to liberate hepatocytes.
The mouse is completely anesthetized long before the surgical procedure commences, and all steps are in compliance with IACUC protocols. This is, obviously, non-survival surgery. The entire blood volume of the mouse is replaced by buffer within 30 seconds upon cannulation.
Much more available at www.mouselivercells.com
- published: 17 May 2011
- views: 13281
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
- Order: Reorder
- Duration: 4:01
- Updated: 28 Jul 2016
- views: 208
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-s...
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-step instructions on the proper way to thaw, plate, and incubate cryopreserved hepatocytes for optimal results.
Reference:
Thawing and Plating Protocol - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Thawing-Cryopreserved-Hepatocytes-Protocol-120815.pdf
Cell Counting Protocol : Trypan Blue Exclusion Method - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Trypan-Blue-Cell-Counting-Protocol.pdf
About Triangle Research Labs:
Since its launch in 2011, Triangle Research Labs, or TRL, has supported scientists by providing high quality hepatocytes for multiple research applications. Based in Research Triangle Park, NC, TRL produces fresh and cryopreserved hepatocytes and hepatic non-parenchymal cells from a variety of species in-house. Additionally, TRL distributes cryopreserved NoSpin HepaRG™ cells and media for Biopredic International, and QuasiVivo® Cell Culture Flow Systems for Kirkstall, Ltd in the US and Canada. TRL utilizes an in-depth understanding of research needs to provide efficient solutions. Visit http://triangleresearchlabs.net/ to learn more.
https://wn.com/Thaw,_Plate,_Incubate_Cryopreserved_Hepatocyte_Thawing_And_Plating_Protocol
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell yield and viability from any lot. This video guide provides step-by-step instructions on the proper way to thaw, plate, and incubate cryopreserved hepatocytes for optimal results.
Reference:
Thawing and Plating Protocol - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Thawing-Cryopreserved-Hepatocytes-Protocol-120815.pdf
Cell Counting Protocol : Trypan Blue Exclusion Method - http://triangleresearchlabs.net/wp-content/uploads/2015/08/Trypan-Blue-Cell-Counting-Protocol.pdf
About Triangle Research Labs:
Since its launch in 2011, Triangle Research Labs, or TRL, has supported scientists by providing high quality hepatocytes for multiple research applications. Based in Research Triangle Park, NC, TRL produces fresh and cryopreserved hepatocytes and hepatic non-parenchymal cells from a variety of species in-house. Additionally, TRL distributes cryopreserved NoSpin HepaRG™ cells and media for Biopredic International, and QuasiVivo® Cell Culture Flow Systems for Kirkstall, Ltd in the US and Canada. TRL utilizes an in-depth understanding of research needs to provide efficient solutions. Visit http://triangleresearchlabs.net/ to learn more.
- published: 28 Jul 2016
- views: 208
Necrosis of Hepatocyte HD
- Order: Reorder
- Duration: 1:22
- Updated: 01 Mar 2016
- views: 238
Video: The process of Hepatocyte cell necrosis.
Notes: Image captured every 30 seconds for 560 minutes by our HT-1 model.
TomoCube's solutions let research...
Video: The process of Hepatocyte cell necrosis.
Notes: Image captured every 30 seconds for 560 minutes by our HT-1 model.
TomoCube's solutions let researchers view live cells, real-time, using holographic microtomography technology.
https://wn.com/Necrosis_Of_Hepatocyte_Hd
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Hepatocyte cell
published: 09 Oct 2015 -
Hepatocyte cell
published: 09 Oct 2015 -
Media1 Transfer of Cryopreserved Hepatocytes
published: 16 Feb 2016 -
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How to Pronounce Hepatocyte
published: 18 Dec 2013 -
How to Pronounce Hepatocyte
published: 08 Nov 2013 -
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Urea Cycle Freeing amides in hepatocytes
published: 15 Oct 2016 -
Media2 Add Cryopreserved Hepatocytes to UCRM
published: 16 Feb 2016 -
How to Pronounce Hepatocytes
This video shows you how to pronounce Hepatocytes
published: 07 Mar 2015
Hepatocyte cell
- Order: Reorder
- Duration: 0:16
- Updated: 09 Oct 2015
- views: 417
- published: 09 Oct 2015
- views: 417
Hepatocyte cell
- Order: Reorder
- Duration: 0:16
- Updated: 09 Oct 2015
- views: 5
- published: 09 Oct 2015
- views: 5
Media1 Transfer of Cryopreserved Hepatocytes
- Order: Reorder
- Duration: 0:16
- Updated: 16 Feb 2016
- views: 43
- published: 16 Feb 2016
- views: 43
POLYPLOIDY IN HEPATOCYTES
- Order: Reorder
- Duration: 3:28
- Updated: 09 Aug 2015
- views: 85
How to Pronounce Hepatocyte
- Order: Reorder
- Duration: 0:07
- Updated: 18 Dec 2013
- views: 92
- published: 18 Dec 2013
- views: 92
How to Pronounce Hepatocyte
- Order: Reorder
- Duration: 0:07
- Updated: 08 Nov 2013
- views: 7
- published: 08 Nov 2013
- views: 7
BIOMYMESIS® Hepatocyte Webinar
- Order: Reorder
- Duration: 29:26
- Updated: 13 Jun 2016
- views: 39
New Technology to Culture Hepatocytes in 3D
New Technology to Culture Hepatocytes in 3D
https://wn.com/Biomymesis®_Hepatocyte_Webinar
Urea Cycle Freeing amides in hepatocytes
- Order: Reorder
- Duration: 2:54
- Updated: 15 Oct 2016
- views: 4
- published: 15 Oct 2016
- views: 4
Media2 Add Cryopreserved Hepatocytes to UCRM
- Order: Reorder
- Duration: 0:48
- Updated: 16 Feb 2016
- views: 31
- published: 16 Feb 2016
- views: 31
How to Pronounce Hepatocytes
- Order: Reorder
- Duration: 0:18
- Updated: 07 Mar 2015
- views: 32
This video shows you how to pronounce Hepatocytes
This video shows you how to pronounce Hepatocytes
https://wn.com/How_To_Pronounce_Hepatocytes
This video shows you how to pronounce Hepatocytes
- published: 07 Mar 2015
- views: 32
-
Webinar - New Technology to Culture Hepatocytes in 3D
Webinar in collaboration with Caltag Medsystems, to present BIOMIMESYS®Hepatocyte
published: 19 Apr 2016 -
-
A New Dimension for Hepatocyte Culture in 3D
Available in a ready-to-use format for 3D culture of hepatocytes and hepatocyte-like cells under physiological conditions representative of the liver microenvironment. The highly porous nature of the BIOMIMESYS scaffold allows for rapid uptake of nutrients, oxygen, etc. into cells to create a reproducible study model for all downstream analytical techniques used with 3D cell culture.
published: 19 Apr 2016 -
Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene
Presenter: Ken Ramos, MD, PhD, PharmB, University of Arizona Polycyclic Aromatic Hydrocarbons
published: 26 Sep 2014 -
Generating In Vivo Relevant Transporter Data Using Transporter Certified Hepatocytes
Presentation by Kenneth R. Brouwer, Ph.D. Originally Aired on February 18, 2014 This webinar highlights the processes that are involved in the certification of cryopreserved human hepatocytes for transporter function and the advantages in using them to characterize a compound's hepatobiliary disposition, transporter interaction potential and overall hepatic clearance. We discuss how Transporter Certified™ hepatocytes can work with a B-CLEAR® Cell-Less kit to provide you with in vivo relevant transporter information. Some frequently asked questions are also discussed. Download Slides: https://www.xenotech.com/scientific-resources/webinar-series/2014/Generating-In-Vivo-Relevant-Transporter-Data-Using.aspx Questions: https://www.xenotech.com/contact-us
published: 13 Apr 2016 -
Hepatic Transporters and Clearance: Emerging Methods to Improve Drug Candidate Selection
Drs. Ayman F. El-Kattan and Kim Brouwer discuss the development of hepatocyte research methods and their application in drug discovery including the importance of basolateral efflux transporters in hepatic drug disposition.
published: 03 Aug 2016 -
Application of Hepatocytes for In Vitro Uptake Assays Webinar
This webinar provides a basic review of concepts applicable to a structure-based approach for the evaluation of hepatic uptake with in vitro hepatocyte experiments. Key concepts discussed in this webinar will include: - Selection of appropriate in vitro study type and design based on predictions from a drug candidate's phys-chem properties - Description of the basic in vitro methodologies using hepatocytes, both suspension and plated, to evaluate drug uptake, namely whole-system versus medium loss, oil-spin method and uptake into plated cells - Discussion of the practical challenges associated with these experiments - Basic review on the estimation of active and passive uptake components from these in vitro hepatocyte experiments - Impact of phys-chem properties, active and...
published: 13 Apr 2016 -
The Quasi Vivo System Bringing In Vivo Relevance to In Vitro Cell Culture Systems
The Quasi Vivo® system includes easy-to-use modular cell culture chamber components which can be connected by flow of media to create physiologically relevant conditions for in vitro cell culture. Primary hepatocytes cultured in the Quasi Vivo® system maintain metabolic activity 2-3 times longer than in static monolayers enabling applications unavailable in standard monlayer hepatocyte cultures. Beyond hepatocytes, the variety of Quasi Vivo® chambers and accessories enables multiple different flow configurations to accommodate a broad range of research questions. Configurations connecting multiple tissue functions enable user-defined “body on a plate” models to be readily engineered. The scale of the culture chambers is equivalent to a standard well of a 24-well culture plate. The scal...
published: 28 Jan 2016 -
Modeling Lipid and Glucose Metabolism Using Human iPSC-derived Hepatocytes
This GEN webinar, sponsored by Cellular Dynamics was originally broadcast Jan 25, 2017. The focus was first on developing assays with human iPSC-derived hepatocytes to interrogate insulin signaling and glucose metabolism—and then on implementing these cells into research programs for the study of lipid dysregulation and metabolic disease state and progression. The study of metabolic disease is changing as limitations of classical in vitro cell models are increasingly evident, causing investigators to search for improved alternatives. Induced pluripotent stem cells (iPSCs) are the logical alternative for advancing basic biology and applied biomedical research through the development of relevant human cell models. Recapitulating native physiological behavior is the ideal scenario for phenot...
published: 26 Jan 2017 -
"From viral hepatitis to hepatocyte transplantation" (Prof. Michael Manns conferència anual)
Professor Michael Manns, recognized expert in the fields of hepatology, gastroenterology and endocrinology at the School of Medicine of Hannover, Germany, has given the 17th Vall d'Hebron University Hospital Annual Conference. In his lecture, titled ""From viral hepatitis to hepatocyte transplantation -- examples for the benefits of scientific networking", Manns talked about the positives outcomes of national and international collaboration in liver diseases research, and the last advances and challenges in transplants.
published: 20 Dec 2013
Webinar - New Technology to Culture Hepatocytes in 3D
- Order: Reorder
- Duration: 32:06
- Updated: 19 Apr 2016
- views: 129
Webinar in collaboration with Caltag Medsystems, to present BIOMIMESYS®Hepatocyte
Webinar in collaboration with Caltag Medsystems, to present BIOMIMESYS®Hepatocyte
https://wn.com/Webinar_New_Technology_To_Culture_Hepatocytes_In_3D
Webinar in collaboration with Caltag Medsystems, to present BIOMIMESYS®Hepatocyte
- published: 19 Apr 2016
- views: 129
Isolation proliferation and differentiation of cord blood along hepatocyte lineage
- Order: Reorder
- Duration: 1:01:27
- Updated: 26 Dec 2012
- views: 93
Isolation proliferation and differentiation of cord blood along hepatocyte lineage Prof Waleed El Masry
Isolation proliferation and differentiation of cord blood along hepatocyte lineage Prof Waleed El Masry
https://wn.com/Isolation_Proliferation_And_Differentiation_Of_Cord_Blood_Along_Hepatocyte_Lineage
A New Dimension for Hepatocyte Culture in 3D
- Order: Reorder
- Duration: 32:06
- Updated: 19 Apr 2016
- views: 41
Available in a ready-to-use format for 3D culture of hepatocytes and hepatocyte-like cells under physiological conditions representative of the liver microenvir...
Available in a ready-to-use format for 3D culture of hepatocytes and hepatocyte-like cells under physiological conditions representative of the liver microenvironment. The highly porous nature of the BIOMIMESYS scaffold allows for rapid uptake of nutrients, oxygen, etc. into cells to create a reproducible study model for all downstream analytical techniques used with 3D cell culture.
https://wn.com/A_New_Dimension_For_Hepatocyte_Culture_In_3D
Available in a ready-to-use format for 3D culture of hepatocytes and hepatocyte-like cells under physiological conditions representative of the liver microenvironment. The highly porous nature of the BIOMIMESYS scaffold allows for rapid uptake of nutrients, oxygen, etc. into cells to create a reproducible study model for all downstream analytical techniques used with 3D cell culture.
- published: 19 Apr 2016
- views: 41
Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene
- Order: Reorder
- Duration: 35:56
- Updated: 26 Sep 2014
- views: 126
Presenter: Ken Ramos, MD, PhD, PharmB, University of Arizona
Polycyclic Aromatic Hydrocarbons
- published: 26 Sep 2014
- views: 126
Generating In Vivo Relevant Transporter Data Using Transporter Certified Hepatocytes
- Order: Reorder
- Duration: 43:53
- Updated: 13 Apr 2016
- views: 54
Presentation by Kenneth R. Brouwer, Ph.D.
Originally Aired on February 18, 2014
This webinar highlights the processes that are involved in the certification of...
Presentation by Kenneth R. Brouwer, Ph.D.
Originally Aired on February 18, 2014
This webinar highlights the processes that are involved in the certification of cryopreserved human hepatocytes for transporter function and the advantages in using them to characterize a compound's hepatobiliary disposition, transporter interaction potential and overall hepatic clearance. We discuss how Transporter Certified™ hepatocytes can work with a B-CLEAR® Cell-Less kit to provide you with in vivo relevant transporter information. Some frequently asked questions are also discussed.
Download Slides: https://www.xenotech.com/scientific-resources/webinar-series/2014/Generating-In-Vivo-Relevant-Transporter-Data-Using.aspx
Questions: https://www.xenotech.com/contact-us
https://wn.com/Generating_In_Vivo_Relevant_Transporter_Data_Using_Transporter_Certified_Hepatocytes
Presentation by Kenneth R. Brouwer, Ph.D.
Originally Aired on February 18, 2014
This webinar highlights the processes that are involved in the certification of cryopreserved human hepatocytes for transporter function and the advantages in using them to characterize a compound's hepatobiliary disposition, transporter interaction potential and overall hepatic clearance. We discuss how Transporter Certified™ hepatocytes can work with a B-CLEAR® Cell-Less kit to provide you with in vivo relevant transporter information. Some frequently asked questions are also discussed.
Download Slides: https://www.xenotech.com/scientific-resources/webinar-series/2014/Generating-In-Vivo-Relevant-Transporter-Data-Using.aspx
Questions: https://www.xenotech.com/contact-us
- published: 13 Apr 2016
- views: 54
Hepatic Transporters and Clearance: Emerging Methods to Improve Drug Candidate Selection
- Order: Reorder
- Duration: 57:16
- Updated: 03 Aug 2016
- views: 342
Drs. Ayman F. El-Kattan and Kim Brouwer discuss the development of hepatocyte research methods and their application in drug discovery including the importance ...
Drs. Ayman F. El-Kattan and Kim Brouwer discuss the development of hepatocyte research methods and their application in drug discovery including the importance of basolateral efflux transporters in hepatic drug disposition.
https://wn.com/Hepatic_Transporters_And_Clearance_Emerging_Methods_To_Improve_Drug_Candidate_Selection
Drs. Ayman F. El-Kattan and Kim Brouwer discuss the development of hepatocyte research methods and their application in drug discovery including the importance of basolateral efflux transporters in hepatic drug disposition.
- published: 03 Aug 2016
- views: 342
Application of Hepatocytes for In Vitro Uptake Assays Webinar
- Order: Reorder
- Duration: 1:01:08
- Updated: 13 Apr 2016
- views: 40
This webinar provides a basic review of concepts applicable to a structure-based approach for the evaluation of hepatic uptake with in vitro hepatocyte experime...
This webinar provides a basic review of concepts applicable to a structure-based approach for the evaluation of hepatic uptake with in vitro hepatocyte experiments.
Key concepts discussed in this webinar will include:
- Selection of appropriate in vitro study type and design based on predictions from a drug candidate's phys-chem properties
- Description of the basic in vitro methodologies using hepatocytes, both suspension and plated, to evaluate drug uptake, namely whole-system versus medium loss, oil-spin method and uptake into plated cells
- Discussion of the practical challenges associated with these experiments
- Basic review on the estimation of active and passive uptake components from these in vitro hepatocyte experiments
- Impact of phys-chem properties, active and passive uptake and metabolism on the estimation of free intracellular drug concentrations
- Brief review of the prediction of in vivo hepatic clearance from in vitro uptake experiments and potential scaling techniques
Download Slides: https://www.xenotech.com/scientific-resources/webinar-series/2013/HepsInVitroUptake.aspx
Questions: https://www.xenotech.com/contact-us
https://wn.com/Application_Of_Hepatocytes_For_In_Vitro_Uptake_Assays_Webinar
This webinar provides a basic review of concepts applicable to a structure-based approach for the evaluation of hepatic uptake with in vitro hepatocyte experiments.
Key concepts discussed in this webinar will include:
- Selection of appropriate in vitro study type and design based on predictions from a drug candidate's phys-chem properties
- Description of the basic in vitro methodologies using hepatocytes, both suspension and plated, to evaluate drug uptake, namely whole-system versus medium loss, oil-spin method and uptake into plated cells
- Discussion of the practical challenges associated with these experiments
- Basic review on the estimation of active and passive uptake components from these in vitro hepatocyte experiments
- Impact of phys-chem properties, active and passive uptake and metabolism on the estimation of free intracellular drug concentrations
- Brief review of the prediction of in vivo hepatic clearance from in vitro uptake experiments and potential scaling techniques
Download Slides: https://www.xenotech.com/scientific-resources/webinar-series/2013/HepsInVitroUptake.aspx
Questions: https://www.xenotech.com/contact-us
- published: 13 Apr 2016
- views: 40
The Quasi Vivo System Bringing In Vivo Relevance to In Vitro Cell Culture Systems
- Order: Reorder
- Duration: 48:40
- Updated: 28 Jan 2016
- views: 425
The Quasi Vivo® system includes easy-to-use modular cell culture chamber components which can be connected by flow of media to create physiologically relevant c...
The Quasi Vivo® system includes easy-to-use modular cell culture chamber components which can be connected by flow of media to create physiologically relevant conditions for in vitro cell culture. Primary hepatocytes cultured in the Quasi Vivo® system maintain metabolic activity 2-3 times longer than in static monolayers enabling applications unavailable in standard monlayer hepatocyte cultures.
Beyond hepatocytes, the variety of Quasi Vivo® chambers and accessories enables multiple different flow configurations to accommodate a broad range of research questions. Configurations connecting multiple tissue functions enable user-defined “body on a plate” models to be readily engineered.
The scale of the culture chambers is equivalent to a standard well of a 24-well culture plate. The scale has proven to be highly practical; being large enough to contain and support 3D cultures and tissue samples, whilst allowing intercommunication between cultures in vitro. This size also provides a balance between large-scale and micro-scale techniques, bringing together advantages of both.
This webinar will introduce the line of QuasiVivo® products, briefly describe the physics of the system, and discuss the various applications to date where QuasiVivo® has proven to enhance physiological relevance of in vitro cell and tissue culture systems.
https://wn.com/The_Quasi_Vivo_System_Bringing_In_Vivo_Relevance_To_In_Vitro_Cell_Culture_Systems
The Quasi Vivo® system includes easy-to-use modular cell culture chamber components which can be connected by flow of media to create physiologically relevant conditions for in vitro cell culture. Primary hepatocytes cultured in the Quasi Vivo® system maintain metabolic activity 2-3 times longer than in static monolayers enabling applications unavailable in standard monlayer hepatocyte cultures.
Beyond hepatocytes, the variety of Quasi Vivo® chambers and accessories enables multiple different flow configurations to accommodate a broad range of research questions. Configurations connecting multiple tissue functions enable user-defined “body on a plate” models to be readily engineered.
The scale of the culture chambers is equivalent to a standard well of a 24-well culture plate. The scale has proven to be highly practical; being large enough to contain and support 3D cultures and tissue samples, whilst allowing intercommunication between cultures in vitro. This size also provides a balance between large-scale and micro-scale techniques, bringing together advantages of both.
This webinar will introduce the line of QuasiVivo® products, briefly describe the physics of the system, and discuss the various applications to date where QuasiVivo® has proven to enhance physiological relevance of in vitro cell and tissue culture systems.
- published: 28 Jan 2016
- views: 425
Modeling Lipid and Glucose Metabolism Using Human iPSC-derived Hepatocytes
- Order: Reorder
- Duration: 59:47
- Updated: 26 Jan 2017
- views: 37
This GEN webinar, sponsored by Cellular Dynamics was originally broadcast Jan 25, 2017. The focus was first on developing assays with human iPSC-derived hepatoc...
This GEN webinar, sponsored by Cellular Dynamics was originally broadcast Jan 25, 2017. The focus was first on developing assays with human iPSC-derived hepatocytes to interrogate insulin signaling and glucose metabolism—and then on implementing these cells into research programs for the study of lipid dysregulation and metabolic disease state and progression.
The study of metabolic disease is changing as limitations of classical in vitro cell models are increasingly evident, causing investigators to search for improved alternatives. Induced pluripotent stem cells (iPSCs) are the logical alternative for advancing basic biology and applied biomedical research through the development of relevant human cell models. Recapitulating native physiological behavior is the ideal scenario for phenotypic screening and target identification—techniques that are paramount to both academic and biopharmaceutical researchers.
https://wn.com/Modeling_Lipid_And_Glucose_Metabolism_Using_Human_Ipsc_Derived_Hepatocytes
This GEN webinar, sponsored by Cellular Dynamics was originally broadcast Jan 25, 2017. The focus was first on developing assays with human iPSC-derived hepatocytes to interrogate insulin signaling and glucose metabolism—and then on implementing these cells into research programs for the study of lipid dysregulation and metabolic disease state and progression.
The study of metabolic disease is changing as limitations of classical in vitro cell models are increasingly evident, causing investigators to search for improved alternatives. Induced pluripotent stem cells (iPSCs) are the logical alternative for advancing basic biology and applied biomedical research through the development of relevant human cell models. Recapitulating native physiological behavior is the ideal scenario for phenotypic screening and target identification—techniques that are paramount to both academic and biopharmaceutical researchers.
- published: 26 Jan 2017
- views: 37
"From viral hepatitis to hepatocyte transplantation" (Prof. Michael Manns conferència anual)
- Order: Reorder
- Duration: 50:27
- Updated: 20 Dec 2013
- views: 326
Professor Michael Manns, recognized expert in the fields of hepatology, gastroenterology and endocrinology at the School of Medicine of Hannover, Germany, has g...
Professor Michael Manns, recognized expert in the fields of hepatology, gastroenterology and endocrinology at the School of Medicine of Hannover, Germany, has given the 17th Vall d'Hebron University Hospital Annual Conference. In his lecture, titled ""From viral hepatitis to hepatocyte transplantation -- examples for the benefits of scientific networking", Manns talked about the positives outcomes of national and international collaboration in liver diseases research, and the last advances and challenges in transplants.
https://wn.com/From_Viral_Hepatitis_To_Hepatocyte_Transplantation_(Prof._Michael_Manns_Conferència_Anual)
Professor Michael Manns, recognized expert in the fields of hepatology, gastroenterology and endocrinology at the School of Medicine of Hannover, Germany, has given the 17th Vall d'Hebron University Hospital Annual Conference. In his lecture, titled ""From viral hepatitis to hepatocyte transplantation -- examples for the benefits of scientific networking", Manns talked about the positives outcomes of national and international collaboration in liver diseases research, and the last advances and challenges in transplants.
- published: 20 Dec 2013
- views: 326
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15:01
Hepatocytes - Liver Histology - Part 1/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010
Hepatocytes - Liver Histology - Part 1/7
Hepatocytes - Liver Histology - Part 1/7
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- published: 07 Sep 2010
- views: 195399
15:01
Hepatocytes - Liver Histology - Part 2/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010
Hepatocytes - Liver Histology - Part 2/7
Hepatocytes - Liver Histology - Part 2/7
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- published: 07 Sep 2010
- views: 100958
9:36
Hepatocytes - Liver Histology - Part 3/7
Watch 700+ videos on Basic Medical Sciences at http://www.DrNajeebLectures.com
published: 07 Sep 2010
Hepatocytes - Liver Histology - Part 3/7
Hepatocytes - Liver Histology - Part 3/7
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- published: 07 Sep 2010
- views: 76416
19:15
Hepatic Physiology 3: Sinusoids & Surrounding Cells
Physiology lecture on the liver. Includes a discussion the the structure and function of t...
published: 16 Jul 2012
Hepatic Physiology 3: Sinusoids & Surrounding Cells
Hepatic Physiology 3: Sinusoids & Surrounding Cells
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- published: 16 Jul 2012
- views: 40283
1:17
How the Body Works : The Architecture of the Liver
The Architecture of the Liver
The liver is the largest organ in the body. Liver tissue...
published: 03 Aug 2007
How the Body Works : The Architecture of the Liver
How the Body Works : The Architecture of the Liver
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- published: 03 Aug 2007
- views: 257201
14:31
Primary mouse hepatocyte isolation
Primary mouse hepatocytes isolation by two step collagenase perfusion method...(www.mousel...
published: 17 Nov 2011
Primary mouse hepatocyte isolation
Primary mouse hepatocyte isolation
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- published: 17 Nov 2011
- views: 23318
0:16
Hepatocyte cell
published: 09 Oct 2015
Hepatocyte cell
Hepatocyte cell
- Report rights infringement
- published: 09 Oct 2015
- views: 417
0:50
Cannulation of mouse portal vein for hepatocyte isolation
This clip details the first step in the surgical procedure for isolation of primary hepato...
published: 17 May 2011
Cannulation of mouse portal vein for hepatocyte isolation
Cannulation of mouse portal vein for hepatocyte isolation
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- published: 17 May 2011
- views: 13281
4:01
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
The handling and care of cryopreserved hepatocytes is crucial to achieving consistent cell...
published: 28 Jul 2016
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
Thaw, Plate, Incubate: Cryopreserved Hepatocyte Thawing and Plating Protocol
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- published: 28 Jul 2016
- views: 208
1:22
Necrosis of Hepatocyte HD
Video: The process of Hepatocyte cell necrosis.
Notes: Image captured every 30 seconds ...
published: 01 Mar 2016
Necrosis of Hepatocyte HD
Necrosis of Hepatocyte HD
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- published: 01 Mar 2016
- views: 238
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0:16
Hepatocyte cell
published: 09 Oct 2015
Hepatocyte cell
Hepatocyte cell
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- published: 09 Oct 2015
- views: 417
0:16
Hepatocyte cell
published: 09 Oct 2015
Hepatocyte cell
Hepatocyte cell
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- published: 09 Oct 2015
- views: 5
0:16
Media1 Transfer of Cryopreserved Hepatocytes
published: 16 Feb 2016
Media1 Transfer of Cryopreserved Hepatocytes
Media1 Transfer of Cryopreserved Hepatocytes
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- published: 16 Feb 2016
- views: 43
3:28
POLYPLOIDY IN HEPATOCYTES
Description
published: 09 Aug 2015
POLYPLOIDY IN HEPATOCYTES
0:07
How to Pronounce Hepatocyte
published: 18 Dec 2013
How to Pronounce Hepatocyte
How to Pronounce Hepatocyte
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- published: 18 Dec 2013
- views: 92
0:07
How to Pronounce Hepatocyte
published: 08 Nov 2013
How to Pronounce Hepatocyte
How to Pronounce Hepatocyte
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- published: 08 Nov 2013
- views: 7
29:26
BIOMYMESIS® Hepatocyte Webinar
New Technology to Culture Hepatocytes in 3D
published: 13 Jun 2016
BIOMYMESIS® Hepatocyte Webinar
BIOMYMESIS® Hepatocyte Webinar
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- published: 13 Jun 2016
- views: 39
2:54
Urea Cycle Freeing amides in hepatocytes
published: 15 Oct 2016
Urea Cycle Freeing amides in hepatocytes
Urea Cycle Freeing amides in hepatocytes
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- published: 15 Oct 2016
- views: 4
0:48
Media2 Add Cryopreserved Hepatocytes to UCRM
published: 16 Feb 2016
Media2 Add Cryopreserved Hepatocytes to UCRM
Media2 Add Cryopreserved Hepatocytes to UCRM
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- published: 16 Feb 2016
- views: 31
0:18
How to Pronounce Hepatocytes
This video shows you how to pronounce Hepatocytes
published: 07 Mar 2015
How to Pronounce Hepatocytes
How to Pronounce Hepatocytes
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- published: 07 Mar 2015
- views: 32
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32:06
Webinar - New Technology to Culture Hepatocytes in 3D
Webinar in collaboration with Caltag Medsystems, to present BIOMIMESYS®Hepatocyte
published: 19 Apr 2016
Webinar - New Technology to Culture Hepatocytes in 3D
Webinar - New Technology to Culture Hepatocytes in 3D
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- published: 19 Apr 2016
- views: 129
1:01:27
Isolation proliferation and differentiation of cord blood along hepatocyte lineage
Isolation proliferation and differentiation of cord blood along hepatocyte lineage Prof W...
published: 26 Dec 2012
Isolation proliferation and differentiation of cord blood along hepatocyte lineage
Isolation proliferation and differentiation of cord blood along hepatocyte lineage
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- published: 26 Dec 2012
- views: 93
32:06
A New Dimension for Hepatocyte Culture in 3D
Available in a ready-to-use format for 3D culture of hepatocytes and hepatocyte-like cells...
published: 19 Apr 2016
A New Dimension for Hepatocyte Culture in 3D
A New Dimension for Hepatocyte Culture in 3D
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- published: 19 Apr 2016
- views: 41
35:56
Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene
Presenter: Ken Ramos, MD, PhD, PharmB, University of Arizona
Polycyclic Aromatic Hydrocarb...
published: 26 Sep 2014
Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene
Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene
- Report rights infringement
- published: 26 Sep 2014
- views: 126
43:53
Generating In Vivo Relevant Transporter Data Using Transporter Certified Hepatocytes
Presentation by Kenneth R. Brouwer, Ph.D.
Originally Aired on February 18, 2014
This webi...
published: 13 Apr 2016
Generating In Vivo Relevant Transporter Data Using Transporter Certified Hepatocytes
Generating In Vivo Relevant Transporter Data Using Transporter Certified Hepatocytes
- Report rights infringement
- published: 13 Apr 2016
- views: 54
57:16
Hepatic Transporters and Clearance: Emerging Methods to Improve Drug Candidate Selection
Drs. Ayman F. El-Kattan and Kim Brouwer discuss the development of hepatocyte research met...
published: 03 Aug 2016
Hepatic Transporters and Clearance: Emerging Methods to Improve Drug Candidate Selection
Hepatic Transporters and Clearance: Emerging Methods to Improve Drug Candidate Selection
- Report rights infringement
- published: 03 Aug 2016
- views: 342
1:01:08
Application of Hepatocytes for In Vitro Uptake Assays Webinar
This webinar provides a basic review of concepts applicable to a structure-based approach ...
published: 13 Apr 2016
Application of Hepatocytes for In Vitro Uptake Assays Webinar
Application of Hepatocytes for In Vitro Uptake Assays Webinar
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- published: 13 Apr 2016
- views: 40
48:40
The Quasi Vivo System Bringing In Vivo Relevance to In Vitro Cell Culture Systems
The Quasi Vivo® system includes easy-to-use modular cell culture chamber components which ...
published: 28 Jan 2016
The Quasi Vivo System Bringing In Vivo Relevance to In Vitro Cell Culture Systems
The Quasi Vivo System Bringing In Vivo Relevance to In Vitro Cell Culture Systems
- Report rights infringement
- published: 28 Jan 2016
- views: 425
59:47
Modeling Lipid and Glucose Metabolism Using Human iPSC-derived Hepatocytes
This GEN webinar, sponsored by Cellular Dynamics was originally broadcast Jan 25, 2017. Th...
published: 26 Jan 2017
Modeling Lipid and Glucose Metabolism Using Human iPSC-derived Hepatocytes
Modeling Lipid and Glucose Metabolism Using Human iPSC-derived Hepatocytes
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- published: 26 Jan 2017
- views: 37
50:27
"From viral hepatitis to hepatocyte transplantation" (Prof. Michael Manns conferència anual)
Professor Michael Manns, recognized expert in the fields of hepatology, gastroenterology a...
published: 20 Dec 2013
"From viral hepatitis to hepatocyte transplantation" (Prof. Michael Manns conferència anual)
"From viral hepatitis to hepatocyte transplantation" (Prof. Michael Manns conferència anual)
- Report rights infringement
- published: 20 Dec 2013
- views: 326
Webinar - New Technology to Culture Hepatocytes in...
Isolation proliferation and differentiation of cor...
A New Dimension for Hepatocyte Culture in 3D...
![Reprogramming of the Hepatocyte Genome by Benzo[α]pyrene](http://web.archive.org./web/20170210095343/https://i.ytimg.com/vi/SABZ4XbFvBk/0.jpg)
Reprogramming of the Hepatocyte Genome by Benzo[α]...
Generating In Vivo Relevant Transporter Data Usin...
Hepatic Transporters and Clearance: Emerging Metho...
Application of Hepatocytes for In Vitro Uptake Ass...
The Quasi Vivo System Bringing In Vivo Relevance t...
Modeling Lipid and Glucose Metabolism Using Human ...
"From viral hepatitis to hepatocyte transplantatio...
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Lyrics list:lyrics
-
Hope, Twista
-
Happy Outside, Omnisoul
Hope
Artist: Twista f/ Cee-Lo
Album: Kamikaze
Song: Hope
Typed by: AArsdam@aol.com
Man I know we had a lot of tragedies lately
I just wanna say rest in peace to Aaliyah
Rest in peace to Left-Eye, rest in peace to Jam Master Jay
And everybody lost in the Twin Towers, and everybody lost period
All we got is hope..
[Verse 1: Twista]
I wish the way I was livin' could stop
Servin' rocks, knowin' the cops is hot when I'm on the block
And I - wish my brother would've made bail
So I won't have to travel six hours to see him in jail
And I - wish that my grandmother wasn't sick
Or that we would just come up on some stacks and hit a lick (I wish)
And I - wish my homies wouldn't have to suffer
When the streets get the upper hand understand we lose a brother
And I - wish I could go deep in the zone
And lift the spirits of the world with words within this song (I wish)
And I - wish I could teach us all to fly
Take away the pain out your hands and help you hold 'em high
And I - wish God had never gave the men power
To be able to hurt the people inside the Twin Towers (I wish)
And I - wish God would've turned they hearts righteous
When they started to take innocent lives and become snipers
But uh - we will never break though they devastate
We shall motivate, and we gotta pray, all we got is faith
Instead of thinkin' about who gon' die today
The Lord is gon' help you feel better so you ain't gotta cry today
Sit at the light so long
And then we gotta move straight forward cause we bite so strong
So when right go wrong
Just say a lil' prayer, get your money man, life goes on... (Let's go)
[Chorus: Cee-Lo]
Cause I'm hopeful, yes I am, hopeful for today
Take this music and use it, let it take you away
And be hopeful, hopeful, and He'll make a way
I know it ain't easy but - that's okay
Just be hopeful
[Verse 2: Twista]
I wish that you would show some love
Instead of hatin' so much when you see some other people comin' up (I wish)
I wish I could teach the world to sing
Write some music and have them trippin' off the joy I bring
Shit - I wish that we can hold hands
Listenin' instead of dissin', lessons from a grown man (I wish)
And I - wish the families that lack but got love
Get some stacks, brand new shack, and a 'Llac that's on dubs
And I - wish we could keep achieving wonders
See the vision of the world through the eyes of Stevie Wonder (I wish)
You feel me - and I hope all the kids eat
And don't nobody in my family see six feet - ya dig?
I hope the mothers stand strong
You can make it whether you with him or your man's gone (I wish)
And I - wish I could give every celly some commissary
And no popo bring the heat on our peace like they did R. Kelly
And I - wish that D.O.C. could scream again
And bullets could reverse and Pac and Biggie breathe again
Shit - and one day they can speak again
I wish that we only saw good news every time we look at CNN
I wish that enemies could talk
And that Super-homie Christopher Reeve could still walk (I wish)
I wish that we could walk the path stay doin' the right thing
Hustle hard so them kids maintain up in the game (Let's go)
[Chorus: Cee-Lo]
Cause I'm hopeful, yes I am, hopeful for today
Take this music and use it, let it take you away
And be hopeful, hopeful, and He'll make a way
I know it ain't easy but - that's okay
Just be hopeful
[Verse 3: Twista]
Wish the earth wasn't so apocaliptic
I try to spread my message to the world the best way that I can give it
We can make it, always so optimistic
If you don't listen, gotta live my life the best way that I can live it
I pray for justice when we go to court
Wish it was all good so the country wouldn't have to go to war
Why can't we kick it and just 'em on
And in the famous words of Mister King, 'why can't we all just get along?'
Hope we can find a better way to shop in peace
And I - hope we find a better way to cop for keys
And I - wish everybody would just stop and freeze
And ask - why are fulfilling these downfalls and these prophecies
You can be wrong if it's you doubtin'
With the faith of a mustard seed, you can move mountains
And only the heavenly father can ease the hurt
Just let it go and keep prayin' on your knees in church (Let's go)
[Chorus: Cee-Lo]
Cause I'm hopeful, yes I am, hopeful for today
Take this music and use it, let it take you away
And be hopeful, hopeful, and He'll make a way
I know it ain't easy but - that's okay
Just be hopeful
(Repeat)
Na na na na na na na na na
Just be hopeful
(Repeat)
Na na na na na na na na na
Na na na na na na na
back
ISIS Brutally Executes 7-Year-Old For Something Children All Over The World Do Every Day
Edit Opposing Views 09 Feb 2017back
House Democrat Files Resolution of Inquiry To Investigate Trump Russian and Business Ties
Edit WorldNews.com 10 Feb 2017
Democrat Rep. Jerrold Nadler from New York filed a "resolution of inquiry" on Thursday in an obscure move to force executive-branch agencies and presidents into sharing records with Congress, as reported by The Washington Post ... “All of this demands investigation, and of course they’ve refused,” Nadler said Thursday at the House Democrats’ annual policy retreat here. “This resolution will force them to confront the issue.”....
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VIDEO: South Africa's Parliament Breaks Out In Brawl During Protest Over President Zuma
Edit WorldNews.com 10 Feb 2017
During a session at South Africa's parliament Thursday, lawmakers were thrown into a chaotic tussle as far-left lawmakers fought with orderlies while interrupting the speech and the main opposition party staged a walk out, according to Reuters ... 400 soldiers joined parliament security outside the building in Cape Town after Zuma authorized the move, in what his opponents described as a "militarization" of parliament....
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New Zealanders race to save whales after 400 stranded
Edit The Associated Press 10 Feb 2017
WELLINGTON, New Zealand (AP) -- New Zealand volunteers formed a human chain in the water at a remote beach on Friday as they raced to save dozens of whales after more than 400 of the creatures beached themselves in one of the worst whale strandings in the nation's history. About three-quarters of the pilot whales were already dead when they were found Friday morning at Farewell Spit at the tip of the South Island ... ....
Cempra's Solithromycin And The Great FDA Echo Chamber
Edit Seeking Alpha 09 Feb 2017
A Question. A few weeks ago, multiple news sources alerted the public about a death caused by a super-bacteria resistant to all known approved antibiotics. A few days before that, the FDA rejected the approval of a new antibiotic. What is it, and why was it rejected? ... CEMP). My thesis, in short ... = Section 1. Introduction = ... c ... (1) ... Lesions included bile ductule proliferation, mixed peribiliary infiltrate, and enlarged vacuolated hepatocytes ... ....
Trump's Intentions to Streamline Drug-Approval Process Fueling Biotech Optimism
Edit Market Watch 07 Feb 2017
PALM BEACH, Florida, February 7, 2017 /PRNewswire via COMTEX/ -- PALM BEACH, Florida, February 7, 2017 /PRNewswire/ -- ... ONVO, +3.51% Q BioMed, Inc. QBIO, -4.33% Galena Biopharma, Inc. GALE, +17.50% Pulmatrix, Inc ... ESPR, +7.42% ... In addition, in pre-clinical experiments uttroside B induced cytotoxicity in all liver cancer cell lines, irrespective of their hepatitis B virus status, while being non-toxic to normal immortalized hepatocytes....
What Does Roundup Do to Your Liver?
Edit Mercola 24 Jan 2017
If you started your day with a bowl of oatmeal, Cheerios or even organic cage-free eggs, there’s a good chance you consumed a small amount of glyphosate residue along with it ... This suggests irreversible hepatocyte damage, as well as large deposition of reticulin fibers containing collagen type III, suggesting liver fibrosis, which is a major risk factor for hepatocarcinogenesis [liver cancer].” How Much Glyphosate Are You Consuming? ... ....
SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes [Cell Biology]>
Edit PNAS 17 Jan 2017
After endocytosis, transmembrane cargo reaches endosomes, where it encounters complexes dedicated to opposing functions ... Microdomains containing endosomal sorting complexes required for transport (ESCRT)-0 component Hrs [hepatocyte growth factor-regulated tyrosine kinase substrate (HGRS-1) in Caenorhabditis elegans] mediate cargo degradation, concentrating ubiquitinated cargo and organizing the activities of ESCRT.... ....
Viking Therapeutics - New Considerations And Updates From Biotech Showcase
Edit Seeking Alpha 13 Jan 2017
Research Coverage- Viking Therapeutics (VKTX). This is meant as a scientific/business development post as to the merits of VKTX. It is well known VKTX is undervalued (by upwards of 40x), but these details will not be discussed here. For a more detailed valuation analysis, see the end of Zacks SCR's post. Background ... They currently have two clinical assets ... NAFLD is defined as accumulation of lipids in >5% of hepatocytes (Masarone 2014)....
Fake Weed Leads to a Real Drug Crisis
Edit Scientific American 11 Jan 2017
Even as states across the U.S. relax laws governing real marijuana, synthetic cannabinoids—commonly known as fake weed, spice or K2—have become increasingly difficult to control. So far this year more than 5,300 incidents involving the drugs have been reported to U.S. poison control offices ... [An edited transcript of the interview follows.] ... We use human liver hepatocytes that metabolize the drug like the liver does ... ....
Gilead Sciences' (GILD) CEO John Milligan Presents at 35th Annual J.P. Morgan Healthcare Conference (Transcript)
Edit Seeking Alpha 09 Jan 2017
Gilead Sciences, Inc. (NASDAQ.GILD). 35th Annual J.P. Morgan Healthcare Conference. January 9, 2017, 01.30 PM ET. Executives. Cory Kasimov - Senior Large Cap Biotech Analyst, J.P. Morgan. John Milligan - President and Chief Executive Officer. Analysts. Cory Kasimov. All right. Good morning, everybody. My name is Cory Kasimov, the senior large cap biotech analyst at J.P. Morgan ... John Milligan. Thanks, Cory ... One is, you have hepatocyte dysfunction ... Q -....
Viking Therapeutics: Barbaric Value
Edit Seeking Alpha 30 Dec 2016
Viking therapeutics (NASDAQ.VKTX) is a recent offshoot of Ligand Pharmaceuticals (NASDAQ.LGND). It has six drugs in its pipeline, three farther along than the others ... Viking's top two candidates are ... VKTX Vitals. Snapshot ... Wainwright ... VKTX Pipeline ... CNAT's candidate, Emricasan, exerts its effects later in the disease process, decreasing the amount of inflammation and apoptosis (cell death) of hepatocytes, or liver cells (CNAT website) ... ....
Pegylated IFN-{alpha} suppresses hepatitis C virus by promoting the DAPK-mTOR pathway [Medical Sciences]>
Edit PNAS 20 Dec 2016
Death-associated protein kinase (DAPK) has been found to be induced by IFN, but its antiviral activity remains elusive. Therefore, we investigated whether DAPK plays a role in the pegylated IFN-α (peg-IFN-α)–induced antiviral activity against hepatitis C virus (HCV) replication. Primary human hepatocytes, Huh-7, and infectious HCV cell culture were used... ....
Here is The Complete Information about Human liver
Edit Community news 11 Dec 2016
Hearts on the body of the human is a large gland has a major role in organ systems. The liver location on the right side on the abdomen (diaphragm muscle). It weighs about 1.5 kg or 3-5% of total body weight ... A substance secreted from the liver is bile ... Each lobule consists of rows of hepatocytes (liver cells) like the spokes of a wheel encircling a vena central. Among hepatocytes are sinusoid (dilated capillaries) ... Reference ... ....
The Complete Information about Human liver
Edit Community news 10 Dec 2016
Hearts on the body of the human is a large gland has a major role in organ systems. The liver location on the right side on the abdomen (diaphragm muscle). It weighs about 1.5 kg or 3-5% of total body weight ... A substance secreted from the liver is bile ... Each lobule consists of rows of hepatocytes (liver cells) like the spokes of a wheel encircling a vena central. Among hepatocytes are sinusoid (dilated capillaries) ... Reference....
Arrowhead Pharmaceuticals Is Oversold
Edit Seeking Alpha 02 Dec 2016
The only ARC-520 trial being conducted in the U.S ... But new information made this scenario impossible. ... However, it is not that simple ... Figure 1 ... Arrowhead Chief Scientific Officer's Oral Presentation, 17th Annual TIDES Conference, May 6, 201 Click to enlarge As shown in Figure 2, EX1's ligand is N-acetylgalactosamine (NAG, pictured as orange balls), which specifically target asialoglycoprotein receptors on HBV-infected hepatocytes ... ....
RG-101 Clinical Hold Offers Investment Opportunity For Regulus Therapeutics
Edit Seeking Alpha 17 Nov 2016
Overview ... Therefore, resolution of the clinical hold (lift or remain) will be determined in late Q1 2017 ... About half of this is excreted through stool and the other half is reabsorbed into circulation, taken up by hepatocytes (liver cells) and then re-excreted as bile ... St ... Given RG-101 changes the liver (the drug is delivered to hepatocytes and antagonizes miR-122), there has always been concerns regarding its long-term safety profile ... ....
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