Moscow, Oct 10 Russian Foreign Minister Sergei Lavrov said relations between Russia and the US have undergone fundamental changes.
Lavrov said Washington policies on Russia are based on "aggressive Russophobia" and their implementations are hurting Russia's national interests and threatening it's security.
"The approach of the NATO (North Atlantic Treaty Organization) and its military infrastructure along our borders, the deployment of the US heavy weapons, and also the sanctions are a manifestation of unfriendly, I would say, hostile actions," said Lavrov.
Earlier this month, Washington suspended negotiations with Moscow on restoring ceasefire in Syria, slamming Russia for a military role in the attacks on the Syrian city of Aleppo.
Russia, in return, has called a halt in cooperation programmes with the US in the nuclear and energy fields.
IANS