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Death receptor 4
Death receptor 4 (DR4), also known as TRAIL receptor 1 (TRAILR1) and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis.
Function
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Interactions
TNFRSF10A has been shown to interact with DAP3.
References
Further reading
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/Death_receptor_4
Latest News for: dr4
Credo to Demonstrate 100G Mixed-Signal DSP for 100G DR1 & 400G DR4 Optical Modules at ...
Nasdaq Globe Newswire 31 Aug 2018
SHENZHEN, China, Aug. 31, 2018 (GLOBE NEWSWIRE) -- Credo, a global innovation leader in high performance, low power connectivity solutions for 100G, 200G, and 400G port enabled networks, today announced it will demonstrate its 100G single lane rate mixed-signal Digital Signal Processing (DSP) solutions to enable 100G per lambda optical connections at the 2018 China International Opto-electronic Exposition (CIOE) ... ....
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