Bremazocine
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Systematic (IUPAC) name | |
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6-ethyl- 3-[(1-hydroxycyclopropyl)methyl]- 11,11-dimethyl- 1,2,3,4,5,6-hexahydro- 2,6-methano- 3-benzazocin-8- ol
or 2-(1-hydroxy- cyclopropylmethyl)- 5-ethyl- 9,9-dimethyl- 2'-hydroxy- 6,7-benzomorphan |
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Clinical data | |
Routes of administration |
Oral |
Legal status | |
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Identifiers | |
CAS Number | 75684-07-0 |
ATC code | none |
PubChem | CID 1223 |
IUPHAR/BPS | 1603 |
ChemSpider | 1186 |
UNII | ISF76M2DBE ![]() |
ChEMBL | CHEMBL1165792 ![]() |
Chemical data | |
Formula | C20H29NO2 |
Molar mass | 315.45 g/mol |
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Bremazocine is a κ-opioid receptor agonist related to pentazocine. It has potent and long-lasting analgesic and diuretic effects.[1] It has 200 times the activity of morphine, but appears to have no addictive properties and does not depress breathing.[2]
See also[edit]
References[edit]
- ^ Dortch-Carnes J, Potter DE (2005). "Bremazocine: a kappa-opioid agonist with potent analgesic and other pharmacologic properties". CNS Drug Reviews. 11 (2): 195–212. doi:10.1111/j.1527-3458.2005.tb00270.x. PMID 16007240.
- ^ Patrick, Graham (2013). An Introduction to Medicinal Chemistry (5th expanded ed.). Oxford University Press. p. 641. ISBN 0199697396.
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See also: Peptide receptor modulators
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