- published: 21 Oct 2015
- views: 6847
Selective serotonin re-uptake inhibitors or serotonin-specific reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
The exact mechanism of SSRIs is unknown. SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having only weak affinity for the norepinephrine and dopamine transporters.
SSRIs are the most widely prescribed antidepressants in many countries. The efficacy of SSRIs in mild or moderate cases of depression has been disputed.
The main indication for SSRIs is major depressive disorder (also called "major depression", "clinical depression" and often simply "depression"). SSRIs are frequently prescribed for anxiety disorders, such as social anxiety disorder, panic disorders, obsessive–compulsive disorder (OCD), eating disorders, chronic pain and occasionally, for posttraumatic stress disorder (PTSD). They are also frequently used to treat depersonalization disorder, although generally with poor results.
Michael Francis Moore (born April 23, 1954) is an American documentary filmmaker, screenwriter, author, journalist, actor, and left-wing political activist. He is the director and producer of Fahrenheit 9/11 (2004), a critical look at the presidency of George W. Bush and the War on Terror, which is the highest-grossing documentary at the American boxoffice of all time and winner of the Palme d'Or. His film Bowling for Columbine (2002), which examines the causes of the Columbine High School massacre, won the Academy Award for Documentary Feature. Both Fahrenheit 9/11 and Sicko (2007), which examines health care in the United States, are among the top ten highest-grossing documentaries. In September 2008, he released his first free movie on the Internet, Slacker Uprising, which documented his personal quest to encourage more Americans to vote in presidential elections. He has also written and starred in the TV shows TV Nation, a satirical newsmagazine television series and The Awful Truth, a satirical show.
I know you and her got something goin on,and I respect that,but you gotta admit,there's something between us..
Everything I want,you got it,
And I must admit that I'm..excited,
That girl aint right for you,
See I'm the type for you,
And what I'd like to do is chill...Feel me?
So let a girl be down and come kick it with me,
No time to play around cus I'm for real baby,
I'm Feelin everything you do,
You know that you're feelin' this too,
So lets..keep it real..
Cus I dont...
I dont care about them other chicks,
I wanna be the one only one that can get close to you,
I dont care about them other chicks,
Cus they aint gonna do all the things Ima do for you,
I dont care who you dealing with,
Just let em know that you found a girl who gone be down for you
So forget about them other chicks,
Just forget about them other chicks.
Like the days when the song used to make you say
Ohhh (ohh) what you do to me,
I'm Feelin you so much I just cant let go (noo) baby see
I'm day dreaming bout your love everyday and I must say that its on and its crazy..
So let a girl be down and come kick it with me,
No time to play around cus I'm for real baby,
I'm Feelin everything you
do,You know that you're feelin' this too,
So lets..keep it real..Keep it reallll..
Boy you got me trippin cus I dont wanna ooh ooh ooh,
Nothing but think about ya, be without ya,best thing gon do..
Wanna be Wanna be ya girl,
You should get with me not her,
Gotta roll wit me come on,and help me sing my song...
Ready ready ready to get it poppin no stoppin so let me know is this what you want..ready ready,ready to get it poppin
I bet we can make it hot so baby come on
(I dont care,