Shuttle America Corporation is a regional airline based in Indianapolis, Indiana,USA. It feeds United Airlines flights at Chicago, and feeds Delta Air Lines flights at Atlanta as Delta Connection and Delta Shuttle.

Shuttle America was established in 1995 by former CEO David Hackett, and began operations on November 12, 1998 as a low-fare commuter airline, headquartered in Windsor Locks, Connecticut, the location of Hartford's Bradley International Airport. Shuttle America's first route was Hartford, Connecticut to Buffalo, New York. Shuttle America got much publicity for their launch because of their "super-low $29 fares". Shuttle America's first aircraft; registered N801SA, was a 50-seat Bombardier Dash 8-300 with leather seats and a very creative and patriotic paint scheme. Shuttle America had rapid growth in its first year, adding more aircraft and destinations.

In 1999, Shuttle America made a controversial move to reach the Boston market. Instead of choosing the busy Logan Airport in East Boston, Shuttle America chose a nearby regional airport, Hanscom Field. Located in Bedford, Massachusetts, just 12 miles (19 km) west of Boston, it had amenities not found at the larger Logan Airport. With free parking, rental cars, and convenience to the I-95 highway, it was promoted as "Hassle-free Hanscom Field". From Hanscom, Shuttle America served Buffalo, LaGuardia Airport in New York, Trenton, New Jersey, and Greensboro, North Carolina via Trenton. At that time Trenton, New Jersey was acting as a hub because of its central location in their route network.