John Fitzgerald Kennedy, the 35th President of the United States, was assassinated at 12:30 p.m. Central Standard Time (18:30 UTC) on Friday, November 22, 1963, in Dealey Plaza, Dallas, Texas. Kennedy was fatally shot while traveling with his wife Jacqueline, Texas governor John Connally, and the latter's wife Nellie, in a Presidential motorcade. Kennedy is the most recent of the four Presidents who were assassinated. He followed Abraham Lincoln, James A. Garfield and William McKinley, all of them fatally shot.

The ten-month investigation by the Warren Commission, 1963–1964, concluded that the President was assassinated by Lee Harvey Oswald acting alone and that Jack Ruby acted alone when he killed Oswald before he could stand trial. These conclusions were initially supported by the American public; however, polls conducted from 1966 to 2004 found that as many as 80 percent of Americans have suspected that there was a plot or cover-up.

Contrary to the Warren Commission, the United States House Select Committee on Assassinations (HSCA) in 1979 concluded that President John F. Kennedy was probably assassinated as a result of a conspiracy. The HSCA found both the original FBI investigation and the Warren Commission Report to be seriously flawed. While agreeing with the Commission that Oswald fired all the shots which caused the wounds to Kennedy and Governor Connally, it stated that there were at least four shots fired and that there was a "high probability" that two gunmen fired at the President. No gunmen or groups involved in the conspiracy were identified by the committee, but the CIA, Soviet Union, organized crime and several other groups were said to be not involved, based on available evidence. The assassination is still the subject of widespread debate and has spawned numerous conspiracy theories and alternative scenarios.

November 22 is the 326th day of the year (327th in leap years) in the Gregorian calendar. There are 39 days remaining until the end of the year.

International Music Day

Year 22 (XXII) was a common year starting on Thursday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Agrippa and Galba (or, less frequently, year 775 Ab urbe condita). The denomination 22 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.