Knockout

A knockout (KO or K.O.) is a fight-ending, winning criterion in several full-contact combat sports, such as boxing, kickboxing, muay thai, mixed martial arts, karate, some forms of taekwondo and other sports involving striking. A full knockout is considered any legal strike or combination thereof that renders an opponent unable to continue fighting.

The term is often associated with a sudden traumatic loss of consciousness caused by a physical blow. Single powerful blows to the head (particularly the jawline and temple) can produce a cerebral concussion or a carotid sinus reflex with syncope and cause a sudden, dramatic KO. Body blows, particularly the liver punch, can cause progressive, debilitating pain that can also result in a KO.

In boxing, kickboxing, etc. a knockout is usually awarded when one participant falls to the canvas and is unable to rise to their feet within a specified period of time, typically because of exhaustion, pain, disorientation, or unconsciousness. For example, if a boxer is knocked down and is unable to continue the fight within a ten-second count, they are counted as having been knocked out and their opponent is awarded the KO victory.

Knockout (disambiguation)

A knockout, in several sports, is a strike that renders an opponent unable to continue fighting.

Knockout may also refer to:

Sports and games

Comics and anime

Literature

Music

Gene knockout

A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism's genes is made inoperative ("knocked out" of the organism). Also known as knockout organisms or simply knockouts, they are used in learning about a gene that has been sequenced, but which has an unknown or incompletely known function. Researchers draw inferences from the difference between the knockout organism and normal individuals.

The term also refers to the process of creating such an organism, as in "knocking out" a gene. The technique is essentially the opposite of a gene knockin. Knocking out two genes simultaneously in an organism is known as a double knockout (DKO). Similarly the terms triple knockout (TKO) and quadruple knockouts (QKO) are used to describe three or four knocked out genes, respectively.

Method

Knockout is accomplished through a combination of techniques, beginning in the test tube with a plasmid, a bacterial artificial chromosome or other DNA construct, and proceeding to cell culture. Individual cells are genetically transfected with the DNA construct. Often the goal is to create a transgenic animal that has the altered gene. If so, embryonic stem cells are genetically transformed and inserted into early embryos. Resulting animals with the genetic change in their germline cells can then often pass the gene knockout to future generations.

Nok

Nok is a village in the south of Kaduna State, Nigeria. The discovery of terracotta figurines at this location caused its name to be used for the Nok culture, of which these figurines are typical, which flourished in Nigeria in the period 1000 BC - 500 AD. The artifacts were discovered in 1943 during mining operations. The archaeologist Bernard Fagg investigated the site, and with the help of locals discovered many other artifacts. Iron smelting furnaces were also found at Nok. Occupation dates far before the first iron smelting. A sample of carbonized wood found in the "main paddock" at Nok in 1951 was dated to around 3660 BC though there are questions about the reliability of this conclusion.

References

NOK

NOK or Nok may refer to:

Cornești, Cluj

Corneşti (Hungarian: Magyarszarvaskend; German: Hirschdorf) is a commune in Cluj County, Romania. It is composed of nine villages: Bârlea (Ónok), Corneşti, Igriţia (Kisigrice), Lujerdiu (Lózsárd), Morău (Móró), Stoiana (Esztény), Tiocu de Jos (Alsótök), Tiocu de Sus (Felsőtök) and Tioltiur (Tötör).

Demographics

According to the census from 2002 there was a total population of 1,809 people living in this town. Of this population, 83.80% are ethnic Romanians, 14.64% are ethnic Hungarians and 1.54% ethnic Romani.

Notes