DCPS

DCPS may refer to:

It might also be used for

DCPS (gene)

Scavenger mRNA-decapping enzyme DcpS is a protein that in humans is encoded by the DCPS gene.

The scavenger mRNA decapping enzymes include Dcp2 and DcpS. DcpS is a scavenger pyrophosphatase that hydrolyses the residual cap structure following 3' to 5' mRNA degradation. DcpS uses cap dinucleotides or capped oligonucleotides as substrates to release m(7)GMP (N7-methyl GMP), while Dcp2 uses capped mRNA as a substrate in order to hydrolyse the cap to release m(7)GDP (N7-methyl GDP). The association of DcpS with 3' to 5' exonuclease exosome components suggests that these two activities are linked and there is a coupled exonucleolytic decay-dependent decapping pathway. The family contains a histidine triad (HIT) sequence in its C-terminal domain, with three histidines separated by hydrophobic residues. The central histidine within the DcpS HIT motif is critical for decapping activity and defines the HIT motif as a new mRNA decapping domain, making DcpS the first member of the HIT family of proteins with a defined biological function.

Duval County, Florida

Duval County is a county located in the State of Florida. As of the 2010 census, the population was 864,263, with a 2014 estimate at 897,698. Its county seat is Jacksonville, with which the Duval County government has been consolidated since 1968. Duval County was established in 1822, and is named for William Pope Duval, Governor of Florida Territory from 1822 to 1834.

Duval County is included in the Jacksonville, FL Metropolitan Statistical Area.

History

This area had been settled by varying cultures of indigenous peoples for thousands of years before European contact. Within the Timucuan Ecological and Historic Preserve in Jacksonville, archeologists have excavated remains of some of the oldest pottery in the United States, dating to 2500 BCE. Prior to European contact, the area was inhabited by the Mocama, a Timucuan-speaking group who lived throughout the coastal areas of northern Florida. At the time Europeans arrived, much of what is now Duval County was controlled by the Saturiwa, one of the most powerful tribes in the region. The area that became Duval County was home to the 16th-century French colony of Fort Caroline, and saw increased European settlement in the 18th century with the establishment of Cowford, later renamed Jacksonville.