Asthma

Asthma (from the Greek ἅσθμα, ásthma, "panting") is a common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm. Common symptoms include wheezing, coughing, chest tightness, and shortness of breath.

Asthma is thought to be caused by a combination of genetic and environmental factors. Its diagnosis is usually based on the pattern of symptoms, response to therapy over time and spirometry. It is clinically classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic) where atopy refers to a predisposition toward developing type 1 hypersensitivity reactions.

Treatment of acute symptoms is usually with an inhaled short-acting beta-2 agonist (such as salbutamol) and oral corticosteroids. In very severe cases, intravenous corticosteroids, magnesium sulfate, and hospitalization may be required. Symptoms can be prevented by avoiding triggers, such as allergens and irritants, and by the use of inhaled corticosteroids.Long-acting beta agonists (LABA) or antileukotriene agents may be used in addition to inhaled corticosteroids if asthma symptoms remain uncontrolled. The occurrence of asthma has increased significantly since the 1970s. In 2011, 235–300 million people globally were diagnosed with asthma, and it caused 250,000 deaths.

Brock Lesnar

Brock Edward Lesnar (/ˈlɛznər/; born July 12, 1977) is an American professional wrestler and former amateur wrestler, professional American football player, and mixed martial artist. He is currently signed to WWE. Lesnar is a four-time WWE (World Heavyweight) Champion, a former UFC Heavyweight Champion, and an NCAA Division I Heavyweight Wrestling Champion, making him the only person to have won a WWE championship, UFC championship, and NCAA championship in a career. He is also a one-time IWGP Heavyweight Champion, making him a five-time world champion in professional wrestling.

After his successful amateur wrestling career at Bismarck State College and the University of Minnesota (106 victories and 5 losses), Lesnar signed with WWE (then the World Wrestling Federation) in 2000. He was assigned to its developmental promotion Ohio Valley Wrestling (OVW), where he was a three-time OVW Southern Tag Team Champion with Shelton Benjamin. After debuting on WWE's main roster in 2002, he won the WWE Championship on three separate occasions with victories over The Rock and Kurt Angle (twice). Lesnar won his first (Undisputed) WWE Championship five months after his main roster debut at the age of 25, becoming the youngest WWE Champion in history. He was also the 2002 King of the Ring and the 2003 Royal Rumble winner, making him the youngest King of the Ring and Royal Rumble winner as well. Following his match with Goldberg at WrestleMania XX, Lesnar left the WWE and pursued a career in the National Football League (NFL). He was named a defensive tackle for the Minnesota Vikings but was cut prior to the start of the 2004–05 season. In 2005, Lesnar returned to professional wrestling and signed with New Japan Pro Wrestling (NJPW), where he won the IWGP Heavyweight Championship in his first match. After a contractual dispute with NJPW, he also wrestled as IWGP Heavyweight Champion in the Inoki Genome Federation (IGF).

The Script

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The Script is an Irish pop rock band formed in 2001. The band comprises guitarist and vocalist Danny O'Donoghue, guitarist and vocalist Mark Sheehan and drummer Glen Power. Based in London after signing to Sony Label Group imprint Phonogenic, the band released its eponymous debut album, The Script, in August 2008, featuring the hit songs "The Man Who Can't Be Moved" and "Breakeven (Falling to Pieces)". The album peaked at number one in Ireland and the UK. Their next three albums, Science & Faith (2010), #3 (2012) and No Sound Without Silence (2014), all topped the album charts in Ireland and the UK, while Science & Faith reached number three in the US. Hit singles from the albums include "For the First Time", "Nothing", "Hall of Fame" and "Superheroes".

The Script's music has been featured in popular television programmes such as 90210, Ghost Whisperer, The Hills, Waterloo Road, EastEnders, Made in Chelsea and The Vampire Diaries. Frontman Danny O'Donoghue was also a coach on The Voice UK for seasons 1 and 2, before leaving the show in order to focus more on the band. The band has won three Meteor Ireland Music Awards, two World Music Awards and have received two Brit Award nominations.