- published: 17 Sep 2009
- views: 129537
fis is the E. coli gene encoding FIS protein. The regulation of this gene is more complex than most other genes in the E. coli genome, as FIS is an important protein which regulates expression of other genes. It is supposed that fis is regulated by H-NS, IHF (protein) and CRP. It also regulates its own expression (autoregulation).
FIS buffers decrease of negative supercoiling in tyrT and rrnA expression. The upstream FIS binding site of rrnA is required for this and it's probable that FIS enables local DNA curvature. See Travers and Muskhelishvili 2005 for more detail.
I've been down, I've been beat
I've been tossed into the street
Making nickels, begging dimes
Just to get my bottle of wine
Some say Life, she's a lady
Kind of soft, kind of shady
I can't tell you Life is rich
She's no lady, she's a bitch
They suck my body out
But then there is no doubt
Gonna pay the devil his dues
Cause I'm so sick of being abused
Eat the rich, eat the rich
Don't you know life is a bitch
Eat the rich, eat the rich
Out of the palace and into the ditch
Steal my money, steal my car
Took my woman and an old guitar
Running crazy, running wild
?? in my eye
Just can't fight the temptation
It's become my inspiration
Gonna get myself an axe
Break some heads and break some backs
They suck my body out
But then there is no doubt
Gonna pay the devil his dues
Cause I'm so sick of being abused
Eat the rich, eat the rich
Don't you know life is a bitch
Eat the rich, eat the rich
Out of the palace and into the ditch
Don't stop me
Eat the rich, eat the rich
Don't you know life is a bitch
Eat the rich, eat the rich
Out of the palace and into the ditch
Eat the rich, eat the rich
Don't you know life is a bitch
Eat the rich, eat the rich
Out of the palace and into the ditch
Out of the palace and into the ditch