Pulse-code modulation

Pulse-code modulation (PCM) is a method used to digitally represent sampled analog signals. It is the standard form of digital audio in computers, Compact Discs, digital telephony and other digital audio applications. In a PCM stream, the amplitude of the analog signal is sampled regularly at uniform intervals, and each sample is quantized to the nearest value within a range of digital steps.

Linear pulse-code modulation (LPCM) is a specific type of PCM where the quantization levels are linearly uniform. This is in contrast to PCM encodings where quantization levels vary as a function of amplitude (as with the A-law algorithm or the μ-law algorithm). Though PCM is a more general term, it is often used to describe data encoded as LPCM.

A PCM stream has two basic properties that determine the stream's fidelity to the original analog signal: the sampling rate, which is the number of times per second that samples are taken; and the bit depth, which determines the number of possible digital values that can be used to represent each sample.

PCM (disambiguation)

PCM or pulse-code modulation is a digital representation of an analog signal.

PCM may also refer to:

Computing

Technology

PCM1

Pericentriolar material 1, also known as PCM1, is a protein which in humans is encoded by the PCM1 gene.

Function

The PCM1 protein was originally identified by virtue of its distinct cell cycle-dependent association with the centrosome complex and microtubules. The protein appears to associate with the centrosome complex during the cell cycle. Dissociation occurs during mitosis when PCM1 is dispersed throughout the cell. Immunolabeling studies performed found that PCM1 was present in centriolar satellites and in electron dense granules between 70 and 100 nm in diameter. These were originally thought to be scattered only around the centrosomes, but further studies proved that PCM1 was also found throughout the cytoplasm.

PCM1 was shown to be essential for cell division because PCM1 antibodies cause cell-cycle arrest when microinjected into fertilized murine eggs. Targeting of centrin, pericentrin and ninein was also dramatically reduced after PCM1 depletion using siRNA, overexpression of PCM1 deletion mutants and PCM1 antibody microinjection. As a result of this depletion, the radial organization of the microtubules was found to be disrupted, but did not appear to effect microtubule nucleation.

Originality

Originality is the aspect of created or invented works by as being new or novel, and thus can be distinguished from reproductions, clones, forgeries, or derivative works. An original work is one not received from others nor one copied from or based upon the work of others.. It is a work created with a unique style and substance. The term "originality" is often applied as a compliment to the creativity of artists, writers, and thinkers. The idea of originality as we know it was invented by Romanticism, with a notion that is often called romantic originality.

The concept of originality is culturally contingent. It became an ideal in Western culture starting from the 18th century. In contrast, at the time of Shakespeare it was common to appreciate more the similarity with an admired classical work, and Shakespeare himself avoided "unnecessary invention".

Originality in law

In law, originality has become an important legal concept with respect to intellectual property, where creativity and invention have manifest as copyrightable works. In the patent law of the United States and most other countries, only original inventions are subject to protection. In addition to being original, inventions submitted for a patent must also be useful and nonobvious.

Original (Cir.Cuz song)

"Original" is a song performed by Norwegian pop duo Cir.Cuz featuring vocals from Emila. It was released on 8 December 2014 as a digital download in Norway. The song peaked at number 28 on the Norwegian Singles Chart.

Track listing

Chart performance

Weekly charts

Release history

References

Original (catamaran)

Original was a catamaran built by Englishman Mayflower Crisp in Rangoon, Burma in the early 19th century.

See also

References